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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
activated sludge respiration inhibition testing
Remarks:
activated sludge, domestic
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1993
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study without detailed documentation

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2000

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test
Deviations:
not specified
GLP compliance:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
Tetrasodium 4-amino-5-hydroxy-3,6-bis[[4-[[2-(sulphonatooxy)ethyl]sulphonyl]phenyl]azo]naphthalene-2,7-disulphonate
EC Number:
241-164-5
EC Name:
Tetrasodium 4-amino-5-hydroxy-3,6-bis[[4-[[2-(sulphonatooxy)ethyl]sulphonyl]phenyl]azo]naphthalene-2,7-disulphonate
Cas Number:
17095-24-8
Molecular formula:
C26H25N5O19S6.4Na
IUPAC Name:
tetrasodium 4-amino-5-hydroxy-3,6-bis[(4-{[2-(sulfonatooxy)ethyl]sulfonyl}phenyl)diazenyl]naphthalene-2,7-disulfonate
Test material form:
solid: particulate/powder

Sampling and analysis

Analytical monitoring:
no

Results and discussion

Effect concentrationsopen allclose all
Duration:
3 h
Dose descriptor:
other: EC20
Effect conc.:
> 5 000 mg/L
Nominal / measured:
not specified
Conc. based on:
test mat.
Basis for effect:
not specified
Duration:
3 h
Dose descriptor:
other: EC80
Effect conc.:
> 5 000 mg/L
Nominal / measured:
not specified
Conc. based on:
not specified
Basis for effect:
not specified
Duration:
3 h
Dose descriptor:
EC50
Effect conc.:
> 5 000 mg/L
Nominal / measured:
not specified
Conc. based on:
not specified
Basis for effect:
not specified

Any other information on results incl. tables

inoculum 1.6 g/l;


The graphical representation of the Dose-response relationship shows that at concentrations of 2500, 5000 and 10000 mg/l none dose-response dependency.


Because of the almost parallel curve becomes the "concentration axis" assumed that up to the concentration of 5000 mg/l safe and at a concentration of 10000 mg/l probably no inhibition has occurred.


 


Inokulum 1.6 g/l; Die grafische Darstellung der
Dosis–Wirkungs–Beziehung zeigt, daß es bei Konzentrationen
von 2500, 5000 und 10000 mg/l keine
Dosis–Wirkungs–Abhängigkeit gibt. Aufgrund des nahezu
parallelen Kurvenverlaufs zur "Konzentrationsachse" wird
davon ausgegangen, dass bis zur Konzentration von 5000 mg/l
sicher und bei einer Konzentration von 10000 mg/l
wahrscheinlich keine Hemmung eingetreten ist.

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
Not toxic for microorganism