Bis(dibutyldithiocarbamato-S,S')copper

Water solubility

Link to relevant study record(s)

Reference

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2012-2013

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

column elution method

Water solubility:

< 1 µg/L

Temp.:

20

pH:

6.5 - 7

Remarks on result:

other: 2 values obtained at 2 different flow rates: 0.22 & 0.73 µg/L, mean value 0.48µg/L

Details on results:

See "Any other information on results incl. tables"

Water solubility results are presented in the following table (results in italics were considered as outlier values):

 

Sample	Time, hours	Test item concentration (µg/L)
		Flow rate 25 mL/h	Flow rate 12.5 mL/h
8	22*	0.8	< LOQ
9	23	0.7	< LOQ
10	24	0.8	< LOQ
11	25	0.6	< LOQ
12	26	0.6	3.99
13	27	0.9	0.24
14	28	1.9	0.15
15	29	8.9	0.26
Mean values for each column	-	0.73	0.22
Mean value		0.48

*Precedent samples not available due to analytical issue

 

 

The mean values obtained at the 2 flow rates experiments are reported below:

 

Flow rate	Results
Column 1 (12.5 mL/h), mean value	0.22 µg/L
Column 2 (25 mL/h), mean value	0.73 µg/L
Mean Value	0.48 µg/L

 

Thus, as estimated by these results, the water solubility of COPPER DIBUTYLDITHIO CARBAMATE can be estimated to be < 1 µg/L.

Conclusions:

Interpretation of results (migrated information): insoluble (< 0.1 mg/L)
The water solubility of COPPER DIBUTYLDITHIO CARBAMATE can be estimated to be < 1 µg/L.

Executive summary:

The water solubility of the test item COPPER DIBUTYLDITHIO CARBAMATE was assessed according to the OECD guideline 105. COPPER DIBUTYLDITHIO CARBAMATE appeared to be very difficult to test under the column method of OECD 105, as analysis revealed some erratic results due to test item uncontrolled particle release. Some results were thus considered as outlier values. The 30% variability a criterion of the guideline was thus not fulfilled; however some results can be used to estimate a water solubility value.

 

The mean values obtained at the 2 flow rates experiments are reported below:

 

Column 1 (12.5 mL/h), mean value: 0.22 µg/L

Column 2 (25 mL/h), mean value: 0.73 µg/L

Mean Value: 0.48 µg/L

 

Thus, as estimated by these results, the water solubility of COPPER DIBUTYLDITHIO CARBAMATE can be estimated to be < 1 µg/L.

 

During the analysis, the temperature was 20 +/- 0.5 °C and the pH was 6.5 to 7.

Description of key information

Assessed according to OECD 105 guideline, the water solubility of COPPER DIBUTYLDITHIO CARBAMATE can be estimated to be < 1 µg/L. 

Key value for chemical safety assessment

Water solubility:

1 µg/L

at the temperature of:

20 °C

Additional information

The water solubility of the test item COPPER DIBUTYLDITHIO CARBAMATE was assessed according to the OECD guideline 105. COPPER DIBUTYLDITHIO CARBAMATE appeared to be very difficult to test under the column method of OECD 105, as analysis revealed some erratic results due to test item uncontrolled particle release. Some results were thus considered as outlier values. The 30% variability a criterion of the guideline was thus not fulfilled; however some results can be used to estimate a water solubility value.

 

The mean values obtained at the 2 flow rates experiments are reported below:

 

Column 1 (12.5 mL/h), mean value: 0.22 µg/L

Column 2 (25 mL/h), mean value: 0.73 µg/L

Mean Value: 0.48 µg/L

 

Thus, as estimated by these results, the water solubility of COPPER DIBUTYLDITHIO CARBAMATE can be estimated to be < 1 µg/L.

 

During the analysis, the temperature was 20 +/- 0.5 °C and the pH was 6.5 to 7.