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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Description of key information

Acutely harmful to fish.

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
42.91 mg/L

Additional information

For risk assessment of ammonium chloride the total topic of ammonia toxicity was regarded. Species mean acute values (SMAV), as given by U.S. EPA (1999) were considered as relevant endpoints. The lowest species mean adjusted total ammonia nitrogen acute value among the 29 fish species acute toxicity results presented by U.S. EPA (1999) was obtained for large rainbow trout (Oncorhynchus mykiss) by Thurston and Russo (1983): LC50 (96 h) at pH 8 = 11.23 mg N/L, i.e. 42.91 mg/L for ammonium chloride. Thurston and Russo (1983) conducted numerous acute toxicity tests with larval, juvenile, yearling, and larger rainbow trout and demonstrated that large rainbow trout were measurably more sensitive than other life stages. Therefore, even if the standard methods use juvenile trout, it appears more relevant to use this species mean acute value of 11.23 mg N/L i.e. 42.91 mg/L ammonium chloride, in order to protect large rainbow trout. For non-salmonids, the lowest species mean adjusted total ammonia nitrogen acute value at pH 8 was obtained for Mountain whitefish (Prosopium williamsoni): LC50 (96h) at pH 8 = 12.11 mg N/L, i.e. 46.27 mg/L for ammonium chloride.