Registration Dossier
Registration Dossier
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EC number: 235-183-8 | CAS number: 12124-97-9
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
- Endpoint:
- bioaccumulation in aquatic species: invertebrate
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- other
- GLP compliance:
- no
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material (migrated information):
Ammonium bromide is an inorganic salt that dissociates to its composite ions in aqueous solutions at environmental pH and temperature. Comparison of the available data on the various bromide salts have shown that the bromide ion is the relevant ion for determination of the toxicological profile with simple cations such as potassium, sodium or ammonium, that are ubiquitous in nature, having little or no influence on the bromide ion properties. It is therefore justified to read-across data from other inorganic bromide salts to ammonium bromide. - Test organisms (species):
- Artemia salina
- Details on test organisms:
- Larvae of Artemia salina
- Total exposure / uptake duration:
- 7 d
- Test temperature:
- 25 °C
- Nominal and measured concentrations:
- 53.11 mg/l
- Type:
- BCF
- Value:
- 0.23 dimensionless
- Endpoint:
- bioaccumulation in aquatic species: fish
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Study period:
- 2007
- Reliability:
- 2 (reliable with restrictions)
- Justification for type of information:
- QSAR prediction
- Principles of method if other than guideline:
- Method: other: calculation
- GLP compliance:
- not specified
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material (migrated information):
Ammonium bromide is an inorganic salt that dissociates to its composite ions in aqueous solutions at environmental pH and temperature. Comparison of the available data on the various bromide salts have shown that the bromide ion is the relevant ion for determination of the toxicological profile with simple cations such as potassium, sodium or ammonium, that are ubiquitous in nature, having little or no influence on the bromide ion properties. It is therefore justified to read-across data from other inorganic bromide salts to ammonium bromide. - Test organisms (species):
- other: unspecified fish
- Type:
- BCF
- Value:
- 1.41 L/kg
- Conclusions:
- Based on the estimated BCF value of 1.41 L/kgwet fish, sodium bromide is considered not to be potentially bioaccumulative.
Referenceopen allclose all
The following equation was used to calculate the bioconcentration factor for fish (BCFfish).
Log BCFfish = 0.85 x log Kow – 0.70
An estimated log Kow value of 1.0 has been used in the calculation.
Therefore:
Log BCFfish = (0.85 x 1.0) – 0.70
Log BCFfish = 0.15
Hence, the BCFfishfor sodium bromide is equal to 1.41 L/kgwet fish.
Description of key information
Bromide ions would be expected to partition to water rather than soils and sediments in the environment given their high water solubility (ca. 90 g per 100 ml for sodium bromide) and the negative charges on the ions. However, a bioconcentration factor for sodium bromide in aquatic invertebrates has been determined experimentally to be 0.23 (Bartolomé M.C.et al., 2005). In addition, a bioconcentration factor for aquatic organisms has been calculated, giving BCFfish = 1.41 L/kgwet fish (D. Carling, 2007).
Key value for chemical safety assessment
- BCF (aquatic species):
- 0.23 dimensionless
Additional information
Ammonium bromide is an inorganic salt that dissociates to its composite ions in aqueous solutions at environmental pH and temperature. Comparison of the available data on the various bromide salts have shown that the bromide ion is the relevant ion for determination of the toxicological profile with simple cations such as potassium, sodium or ammonium, that are ubiquitous in nature, having little or no influence on the bromide ion properties. It is therefore justified to read-across data from other inorganic bromide salts to ammonium bromide.
Bromide ions would be expected to partition to water rather than soils and sediments in the environment given their high water solubility (ca. 90 g per 100 ml for sodium bromide) and the negative charges on the ions. However, a bioconcentration factor for sodium bromide in aquatic invertebrates has been determined experimentally to be 0.23 (Bartolomé M.C.et al., 2005). In addition, a bioconcentration factor for aquatic organisms has been calculated, giving BCFfish = 1.41 L/kgwet fish (D. Carling, 2007).
Given this data it is considered that there is minimal risk of bioaccumulation and of secondary poisoning to the aquatic compartment.
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