Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 233-881-7 | CAS number: 10411-92-4
Melting point / freezing point
Administrative data
Link to relevant study record(s)
- Endpoint:
- melting point/freezing point
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- other:
- Justification for type of information:
- JUSTIFICATION FOR DATA WAIVING
Supporting literature data on an analogue shows that the freezing point is expected to fall much below -20°C.
Therefore NO new experimental study is deemed necessary for the parent substance. - Reason / purpose for cross-reference:
- data waiving: supporting information
- Endpoint:
- melting point/freezing point
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- secondary literature
- Remarks:
- Literature data. Original source not checked. No data on substance composition.
- Justification for type of information:
- Read-across is justified as data relates to mixture of isomers (cis/trans) of the present dossier substance (monoconstituent, cis-isomer).
- Qualifier:
- according to guideline
- Guideline:
- other: ASTM D-1015
- GLP compliance:
- no
- Melting / freezing pt.:
- < -50 °C
- Conclusions:
- Freezing point <-20°C.
No further testing necessary. - Executive summary:
Published literature data for submission to the US-EPA provides a limit value of <-50°C for the substance 4-tert-Butylcyclohexyl acetate, with reference to guideline.
Read-across is justified as source data is available for mixture of cis and trans isomers, and target contains mainly (>80%) the cis isomer.
Referenceopen allclose all
Description of key information
Freezing point <-20°C.
No further testing necessary.
Key value for chemical safety assessment
- Melting / freezing point at 101 325 Pa:
- -20 °C
Additional information
No data is available on the substance itself. However, published literature data on an analogue (mixture of isomers) provides a limit value of <-50°C. Despite reliability could not be assigned, this data is considered sufficient for purpose, as no further testing is required below -20°C. As no significant difference is anticipated with the present dossier monoconstituent substance, the read-across is considered justified.
As risk assessment requires a figure in the above "key value" box (no < or > sign accepted), this threshold value will be used as default data for CSA purpose.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
