Palladium dinitrate

Hydrolysis

Administrative data

Endpoint:

hydrolysis

Type of information:

experimental study

Adequacy of study:

supporting study

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

guideline study with acceptable restrictions

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2003

Report date:

2003

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

OECD Guideline 111 (Hydrolysis as a Function of pH)

Deviations:

not specified

Test guideline 2

Qualifier:

according to guideline

Guideline:

EU Method C.7 (Degradation: Abiotic Degradation: Hydrolysis as a Function of pH)

Deviations:

not specified

GLP compliance:

yes (incl. QA statement)

Test material

Test material information

Constituent 1

Reference substance name:

Palladium(II) nitrate dihydrate

Cas Number:

32916-07-7

Molecular formula:

2NO3.Pd.2H2O

IUPAC Name:

Palladium(II) nitrate dihydrate

Details on test material:

40.1% palladium

Radiolabelling:

no

Study design

Analytical monitoring:

yes

Details on sampling:

tests carried out at pH 4,7 and 9

Buffers:

pH 4: citrate - hydrochloric acid. pH 7: potassium dihydrogen phosphate - disodium hydrogen phosphate. pH 9: boric acid-potassium chloride-sodium hydroxide

Details on test conditions:

Details on test conditions: Substance dissolved in 2L of standard buffer solutions at 50°C +- 0.5°C

Duration of test

Duration of test 1

Duration:

5 d

pH:

4

Temp.:

50 °C

Initial conc. measured:

923 mg/L

Duration of test 2

Duration:

5 d

pH:

7

Temp.:

50 °C

Initial conc. measured:

224 mg/L

Duration of test 3

Duration:

5 d

pH:

9

Temp.:

50 °C

Initial conc. measured:

< 25 mg/L

Number of replicates:

2

Positive controls:

not specified

Negative controls:

not specified

Results and discussion

Preliminary study:

At pH 4 < 10% of the test item has been hydrolysed after 5 days at 50°C. At pH 7 and 9 more than 50 % of the test item had been hydrolysed within 2.4 h at 50°C. Thus additional testing at pH 4, 7 and 9 is not required.

Applicant's summary and conclusion

Conclusions:

At pH 4 < 10% of the test item was hydrolysed after 5 days at 50°C. At pH 7 and 9 more than 50 % of the test item had been hydrolysed within 2.4 h at 50°C. Thus additional testing at pH 4, 7 and 9 was not required.

Executive summary:

This is a GLP compliant, guideline study and is considered suitable for assessment. At pH 4 < 10% of the test item has been hydrolysed after 5 days at 50°C. At pH 7 and 9 more than 50 % of the test item had been hydrolysed within 2.4 h at 50°C. Thus additional testing at pH 4, 7 and 9 is not required.