Registration Dossier
Registration Dossier
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EC number: 232-462-6 | CAS number: 8047-15-2
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
No data gaps were identified. The available data are adequate for risk assessment and classification and labelling purposes.
Migrated from Short description of key information:
The aim of the sensitization study was to assess the allergenic potential of Quillaja Liquid Agri QL Agri 35-15 according to the test method described by EV Buehler, (OECD 406).
Following dose levels were used: 100% w/v solution of Quillaja Liquid Agri QL Agri 35-15 in the the induction phase, 100% w/v solution of Quillaja Liquid Agri QL Agri 35-15 in the challenge phase.
Quillaja Liquid Agri QL Agri 35-15 didn't cause skin sensitization on the Guinea pigs skin. Animals behaved normally and their external appearance was not influenced by the treatment.
Justification for selection of skin sensitisation endpoint:
One reliable study is available.
Respiratory sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Justification for classification or non-classification
In an OECD Guideline 406 study (Skin Sensitisation: Bühler Test), no signs of skin sensitisation were observed.
According to the CLP Regulation (EU GHS Regulation (EC) No 1272/2008) no classification and labelling is required for skin sensitisation of Quillaja saponaria ext..
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