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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Hydrolysis

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
hydrolysis
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
other:
Justification for type of information:
‘Hydrolysis’ refers to the “Decomposition or degradation of a chemical by reaction with water”, and is a concept that is relevant for organic compounds, that may or may not decompose in water, e.g. by abiotic degradation. The need for testing may be waived if “The substance is highly insoluble in water), or if “The substance is readily biodegradable”.
For metals and inorganic substances (germanium), the chemical safety assessment is based on the (bioavailable) concentrations of the ion, e.g. Ge2+,…,. For the bioavailable ionic concentration of the metal elements (MeX+), physicochemical processes like decomposition and degradation by reaction with water are not relevant. The applied pooling of all elemental-metal ions together, can be considered as a worst-case assumption for the assessment. In general, (abiotic) degradation is an irrelevant process for inorganic substances that are assessed on an elemental basis.

Description of key information

‘Hydrolysis’ refers to the “Decomposition or degradation of a chemical by reaction with water”, and is a concept that is relevant for organic compounds, that may or may not decompose in water, e.g. by abiotic degradation. The need for testing may be waived if  “The substance is highly insoluble in water), or if “The substance is readily biodegradable”.

For metals and inorganic substances (germanium), the chemical safety assessment is based on the (bioavailable) concentrations of the ion, e.g. Ge2+,…,. For the bioavailable ionic concentration of the metal elements (MeX+), physicochemical processes like decomposition and degradation by reaction with water are not relevant. The applied pooling of all elemental-metal ions together, can be considered as a worst-case assumption for the assessment. In general, (abiotic) degradation is an irrelevant process for inorganic substances that are assessed on an elemental basis.

Key value for chemical safety assessment

Additional information