4-hydroxy-2,5-dimethylfuran-2(3H)-one

Surface tension

Link to relevant study record(s)

Reference

Endpoint:

surface tension

Type of information:

experimental study

Adequacy of study:

key study

Study period:

experimental dates: 29 Nov. 2016

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Remarks:

The study was conducted according to an internationally recognised method, and under GLP, with no deviation. The substance is adequately characterised. Therefore full validation applies.

Qualifier:

according to guideline

Guideline:

OECD Guideline 115 (Surface Tension of Aqueous Solutions)

Version / remarks:

27 July 1995

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.5 (Surface Tension)

Version / remarks:

Regulation (EC) N°440/2008

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Remarks:

Landesamt für Umwelt, Wasserwirtschaft und Gewerbeaufsicht (inspected on 13 & 14 October 2014, 2010 / signed on 08 April 2015)

Type of method:

plate method

Key result

Surface tension:

71.78 mN/m

Temp.:

20 °C

Conc.:

1 g/L

Control

Measured Values Negative Control (HPLC water): 73.01 mN/m at 19.6°C (SD=0.07, n=10)

Literature value for the surface tension of H2O at 19.5 °C: 72.83 mN/m (taken from Vargaftik et al., “International Tables of the Surface Tension of Water”, J. Phys. Chem. Ref.Data 12, 817, 1983).

The surface tension of the negative control was determined with 73.01 mN/m, therefore showing a difference of 0.25% from the stated literature value. The difference lies within the accepted range of 1% deviation from literature value. Therefore, no correction factor for water is deemed necessary.

Test item

The test item solution was held at constant temperature (20.0 ± 0.2 °C). 59 minutes after conclusion of the first measurement series, a second measurement series was performed for verification purposes.

Measured Values Test Item First Series: 71.78 mN/m at 20.0°C (SD=0.05, n=10)

Measured Values Test Item Second Series: 70.36 mN/m at 20.2°C (SD=0.08, n=10)

During the specified period of time, no significant changes in the surface tension were detected. Values ranging from 70.18 mN/m to 71.82 mN/m were recorded showing no significant variations. The values of the single determinations show no significant difference (less than 5 % between mean values of the two measurement series). Therefore, no additional measurement series was required.

Conclusions:

According to EU A5 criteria, as the result is above the threshold value of 60 mN/m, the substance is considered to have NO surface-active potential under the experimental conditions.

Executive summary:

The surface tension of the test substance was determined under GLP according to OECD 115/EU A5 guideline, with the plate method.

After check with water as negative control, a series of ten determinations was performed in duplicate on a 1 g/L sample solution, and repeated after a 59 minutes standing period for time-dependency.

Results were repeatable, so the value of 71.78 mN/m, from the first test series, was retained.

Description of key information

According to EU A5 criteria, as the result is above the threshold value of 60 mN/m, the substance is considered to have NO surface-active potential under the experimental conditions.

Key value for chemical safety assessment

Surface tension:

71.78

in mN/m at 20°C and concentration in mg/L:

1 000

Additional information

A fully reliable experimental study, conducted according to a recognized OECD/EC method and under GLP, is available. Therefore, it is considered as a key study, and the result is retained as key data.