Registration Dossier
Registration Dossier
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EC number: 221-130-6 | CAS number: 3010-02-4
Dissociation constant
Administrative data
- Endpoint:
- dissociation constant
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Authoritative secondary source
Data source
Reference
- Reference Type:
- secondary source
- Title:
- Reaxys ID 969468
- Author:
- Reaxys
- Year:
- 2 015
- Bibliographic source:
- Copyright © 2015 Reed Elsevier Properties SA. All rights reserved. Authorized use only. Reaxys® and the Reaxys® trademark are owned and protected by Reed Elsevier Properties SA and used under license.
- Report date:
- 2015
Materials and methods
Test guideline
- Guideline:
- other: no data
- GLP compliance:
- not specified
Test material
- Reference substance name:
- (diethylamino)acetonitrile
- EC Number:
- 221-130-6
- EC Name:
- (diethylamino)acetonitrile
- Cas Number:
- 3010-02-4
- Molecular formula:
- C6H12N2
- IUPAC Name:
- 2-(diethylamino)acetonitrile
- Details on test material:
- - Name of test material (as cited in study report): 2-(diethylamino)acetonitrile
- Analytical purity: pure
Constituent 1
Results and discussion
- Dissociating properties:
- yes
Dissociation constantopen allclose all
- pKa:
- 4.55
- Temp.:
- 25 °C
- Remarks on result:
- other: potentiometric; Kreevoy,M.M.; Oh,S.-W.; Journal of the American Chemical Society; vol. 95; (1973); p. 4805 - 4810,
- pKa:
- 4.55
- Temp.:
- 25 °C
- Remarks on result:
- other: potentiometric; Stevenson; Williamson; Journal of the American Chemical Society; vol. 80; (1958); p. 5943,5946
- pKa:
- 4.5
- Temp.:
- 29 °C
- Remarks on result:
- other: potentiometric; Soloway; Lipschitz; Journal of Organic Chemistry; vol. 23; (1958); p. 613
- pKa:
- 4
- Remarks on result:
- other: potentiometric; Stewart; Cook; Journal of the American Chemical Society; vol. 50; (1928); p. 1980
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
