4-[3-(4-chlorophenyl)-4,5-dihydro-1H-pyrazol-1-yl]benzenesulphonamide

Density

Link to relevant study record(s)

Reference

Endpoint:

relative density

Type of information:

experimental study

Adequacy of study:

key study

Study period:

March 28th, 2018

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

test procedure in accordance with generally accepted scientific standards and described in sufficient detail

Qualifier:

according to guideline

Guideline:

OECD Guideline 109 (Density of Liquids and Solids)

Version / remarks:

adopted: 2 October 2012

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

pycnometer method

Type:

relative density

Density:

1.35

Temp.:

20 °C

DETERMINATION OF DENSITY OF TEST ITEM

Replication Number	Weight of Test Item (g)	Volume of Pycnometer (ml)	Volume of Wetting Solution (ml)	Density of Test Item (g/ml)	SD (±)	RSD (%)
1	10.5501	49.9535	42.1168	1.3462	-	-
2	10.7024	49.2118	41.2775	1.3489
Mean	10.6262	49.5826	41.6971	1.3476	0.002	0.15

DETERMINATION OF WATER EQUIVALENT AND VOLUME OF PYCNOMETER AT 20 °C

Replication Number	Weight of Empty Pycnometer (g)	Weight of Pycnometer with Water (g)	Water Equivalent Weight (g)	Volume of the Pycnometer at 20 °C (ml)
1	42.7215	92.5751	49.8536	49.9535
2	42.1630	91.2764	49.1134	49.2118
Mean	42.4422	91.9257	48.4835	50.5847

DETERMINATION OF DENSITY OF WETTING SOLUTION

Replication Number	Weight of Empty Pycnometer (g)	Weight of Pycnometer with Wetting Solution (g)	Weight of Wetting Solution (g)	Volume of Pycnometer (ml) at 20 °C	Density of Wetting Solution (g/ml)
1	42.7215	85.7706	43.0491	49.9535	0.8618
2	42.1630	84.5093	42.3463	49.2118	0.8605
Mean	42.4422	85.1399	42.6977	49.5826	0.8611

DETERMINATION OF VOLUME OF WETTING SOLUTION

Replication Number	Weight of Empty Pycnometer (g)	Weight of Pycnometer with Test Item and Wetting Solution (g)	Weight of Pycnometer with Test Item (g)	Weight of Test Item (g)	Volume of Wetting Solution (ml)
1	42.7215	89.5679	53.2716	10.5501	42.1168
2	42.1630	88.3847	52.8654	10.7024	41.2775
Mean	42.4422	88.9763	53.0685	10.6262	41.6971

Conclusions:

1.35 at 20 °C

Executive summary:

The density of the substance was determined as per the OECD guideline for the testing of chemicals, No. 109, “Density of Liquids and Solids”.

The empty pycnometer, pycnometer with water, pycnometer with wetting solution, pycnometer with 2/3 of test item and pycnometer with 2/3 of test item with wetting solution were weighed in order to calculate the water equivalent and the volume of the pycnometer. The density of the wetting solution, volume of wetting solution and density of the test item were calculated from the water equivalent and the volume of the pycnometer. The test was performed at 20 °C under thermostatic conditions. The following values were obtained: 1.3462 g/ml and 1.3489 g/ml for replicates R1 and R2, respectively. The calculated mean density value of the replicates was found to be 1.3476 g/ml with 0.15 % of RSD, corresponding to a relative density of 1.35.

Conclusion

The relative density of the substance was found to be 1.35 at 20 °C.

Description of key information

1.35 at 20 °C

Key value for chemical safety assessment

Relative density at 20C:

1.35

Additional information

OECD 109 - pycnometer