Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 219-323-5 | CAS number: 2414-98-4
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- the study does not need to be conducted because the substance is hydrolytically unstable at pH 4, 7 and 9 (half-life less than 12 hours)
- Endpoint:
- water solubility
- Type of information:
- other: handbook
- Adequacy of study:
- key study
- Study period:
- not known
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: A number of the references are regarded as reliable secondary sources by OECD or within the REACH guidance on information requirements and chemical safety assessment.
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- no data. Information from reliable handbook sources
- GLP compliance:
- not specified
- Remarks:
- Information from reliable handbook sources
- Type of method:
- other: no data. Information from reliable handbook sources
- Water solubility:
- 789 g/L
- Temp.:
- 20 °C
- pH:
- 7
- Details on results:
- Miscible/completely soluble.
- Conclusions:
- Interpretation of results (migrated information): miscible
Substance is fully miscible in water in all proportions - Executive summary:
A large number of reliable handbook sources consistently report that ethanol is fully miscible in water.
- Endpoint:
- water solubility
- Type of information:
- other: handbook source
- Adequacy of study:
- supporting study
- Study period:
- not known
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Secondary source (handbook) that is widely regarded as reliable. Origin of data is cited.
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- no data. Information from reliable handbook source
- GLP compliance:
- not specified
- Type of method:
- other: no data. Information from reliable handbook source
- Water solubility:
- ca. 789 000 mg/L
- Temp.:
- 25 °C
- pH:
- 7
- Details on results:
- Figure shown represents density of substance and a 'nominal' value for complete solubility.
pKa: 16 at 25 °C is cited. - Conclusions:
- Interpretation of results (migrated information): miscible
Ethanol is fully water miscible in water. - Executive summary:
A reliable secondary source reports that ethanol is fully miscible in water in all proportions.
Referenceopen allclose all
Temperature and pH nominal values - not quoted in data sources. Value quoted for solubility is a nominal value equivalent to the density to represent full miscibility with water. Described as infinite solubility of ethanol in water and water in ethanol.
Description of key information
Magnesium ethanolate is hydrolytically unstable at pH 4, 7, and 9 and the halfe-life is approx. 1 minute, therefore the endpoint is waived for Magnesium ethanolate.
The hydrolysis product ethanol is completely miscible in water at 20°C (water solubility 789 g/l) . The hydrolysis product magnesium hydroxide is poorly soluble at 20°C (water solubility ca 1.78 mg/l ).
Key value for chemical safety assessment
- Water solubility:
- 1.78 mg/L
- at the temperature of:
- 20 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
