Methyl 3,4,5-trimethoxybenzoate

Guidance on Safe Use

First-aid measures

Description of first aid measures:

First-aid measures after inhalation : Remove person to fresh air and keep comfortable for breathing. If breathing stops, give artificial respiration.

First-aid measures after skin contact : Wash off with soap and plenty of water.

First-aid measures after eye contact : Rinse eyes with water as a precaution.

First-aid measures after ingestion : Call a poison center or a doctor if you feel unwell. Never give anything by mouth to an unconscious person. Rinse mouth with water.

Indication of any immediate medical attention and special treatment needed:

Treat symptomatically

Fire-fighting measures

1. Extinguishing media

Suitable extinguishing media : Water spray. Dry powder. Alcohol resistant foam. Carbon dioxide.

2. Special hazards arising from the substance or mixture

Hazardous decomposition products in case of fire: Toxic fumes may be released. Carbon oxides (CO, CO2).

3. Advice for firefighters

Protection during firefighting : Do not attempt to take action without suitable protective equipment. If necessary, use an autonomous respiratory protection for the fire control. Complete protective clothing.

Accidental release measures

1. Personal precautions, protective equipment and emergency procedures

General measures : Avoid generating dusty conditions. Avoid inhaling vapors, fogs of pulverizing or gases.

1.1. For non-emergency personnel

Emergency procedures : Ventilate spillage area.

1.2. For emergency responders

Protective equipment : Do not attempt to take action without suitable protective equipment.

2. Environmental precautions

Avoid release to the environment. Prevent entry to sewers and public waters.

3. Methods and material for containment and cleaning up

Methods for cleaning up : Mechanically recover the product. Sweep up or shovel. Keep in suitable and closed containers for disposal.

Other information : Dispose of materials or solid residues at an authorized site.

Handling and storage

1. Precautions for safe handling

Precautions for safe handling : Provide adequate ventilation where dust is formed. Wear personal protective equipment. Normal measures for preventive fire protection.

Hygiene measures : Do not eat, drink or smoke when using this product. Always wash hands after handling the product.

2. Conditions for safe storage, including any incompatibilities

Storage conditions : Store in a dry place. Store in a closed container. Store in a well-ventilated place. Keep cool.

This substance is handled under Strictly Controlled Conditions in accordance with REACH regulation Article 18(4) for transported isolated intermediate. Site documentation to support safe handling arrangements including the selection of engineering, administrative and personal protective equipment controls in accordance with risk-based management system is available at each site. Written confirmation of application of Strictly Controlled Conditions has been received from every Downstream user of the intermediate.

Transport information

Shipping

SpecialProvisions

Shipping

Remarks

Marine transport (UN RTDG/IMDG)

Shipping

Remarks

Shipping

Remarks

SpecialProvisions

Exposure controls / personal protection

Exposure controls:

Appropriate engineering controls:

Ensure good ventilation of the work station. Handle in accordance with good industrial hygiene and safety practice.

Hand protection:

Manipulate with gloves. Gloves have to be controlled before the use. Use a technique of withdrawal of gloves suited to avoid that the skin contacts

the product (i.e. without touching the outside surface of the glove). Throw gloves contaminated after the use according to the current laws and to the

good practices of laboratory. Wash and dry hands. The selected gloves have to satisfy the specifications of the EU Directive 89 / 686 / EEC and in the standard IN 374 which derives from it.

Eye protection:

Facial protection and safety goggles. Use an equipment of protection of eyes, tested and approved according to the current governmental standards, such as NIOSH (US) or IN 166 (EU).

Skin and body protection:

Wear suitable protective clothing. Choose body protection in relation to its type, to the concentration and amount of dangerous substances, and to the specific work-place. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.

Respiratory protection:

No personal breathing protective equipment is normally required. Wear a mask for dusty type N95(US) or type P1(EN143). Use approved material for standards such as NIOSH-US) or CEN(EU).

Environmental exposure controls:

Avoid release to the environment.

This substance is handled under Strictly Controlled Conditions in accordance with REACH regulation Article 18(4) for transported isolated intermediate. Site documentation to support safe handling arrangements including the selection of engineering, administrative and personal protective equipment controls in accordance with risk-based management system is available at each site. Written confirmation of application of Strictly Controlled Conditions has been received from every Downstream user of the intermediate.

Stability and reactivity

Incompatible materials: Strong oxidizers

Disposal considerations

Waste treatment methods : Offer surplus and non-recyclable solutions to a licensed disposal company. Contact a licensed professional waste disposal service to dispose of this material. Dispose of contaminated packaging as unused product.