Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 216-074-4 | CAS number: 1490-04-6
Endpoint summary
Administrative data
Description of key information
Additional information
5.1.2 Hydrolysis
With regard to its chemical structure of menthol, no hydrolysis property is expected under environmental conditions.
5.2.1 Biodegradation
Ready biodegradability:
Read-across:
A closed bottle test comparable to OECD TG 301 D under aerobic conditions was performed and after 28 days 92 % of D-Menthol (CAS no. 15356 -60-2) was degraded in a test with an initial concentration of 0.84 mg/l and 76 % of D-Menthol was degraded in a test with an initial concentration of 2.01 mg/l. Therefore, D-Menthol is considered being readily biodegradable (Haarmann & Reimer, 2002).
Inherent biodegradability:
A test on inherent biodegradation comparable to OECD TG 302 B was performed with a duration of 5 days. 95.1 % of DL-Menthol (CAS no. 1490 -04 -6) was degraded during the test period. Therefore, Menthol is considered being inherent biodegradable (Pitter, 1976).
5.3.1 Bioaccumulation
In a bioaccumulation test, corresponding to OECD Guideline 305C, a BCF of <0.5 - 15 at 0.2 mg/L and <4.6 - 11 at 0.02 mg/L test concentration for menthol was determined with Oryzias latipes as test organism within 6 weeks (MITI 1996).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
