Registration Dossier
Registration Dossier
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EC number: 215-836-3 | CAS number: 1424-00-6
Hydrolysis
Administrative data
Link to relevant study record(s)
Description of key information
Estimation based on the chemical structure.
General Physical Chemistry, Schering AG, Berlin. Study report No. A01734 (APC 88/00), dated 2000-10-10.
Result: Mesterolone is expected to be hydrolytically stable in the pH region 4 to 9.
Key value for chemical safety assessment
Additional information
The test substance molecule and all of its functional groups belong to a class of substances that are generally resistant to hydrolysis, e.g.:
alkanes, alkenes, alkynes, benzenes/biphenyls, polycyclic aromatic hydrocarbons, heterocyclic polycyclic aromatic hydrocarbons, halogenated aromatics, aromatic nitro compounds, aromatic amines, alcohols, phenols, glycols, ethers, aldehydes, ketones, carboxylic acids, sulfonic acids
(for reference see: Lyman, W. J.; Reehl, W. F.; Rosenblatt, D. H.; Handbook of Chemical Property Estimation Methods, McGraw-Hill New York 1982, p. 7-4).
Therefore, mesterolone is to be considered hydrolytically stable in the relevant pH region 4 - 9.
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