Registration Dossier
Registration Dossier
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EC number: 215-282-2 | CAS number: 1317-80-2
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
No reliable acute toxicity data on aquatic invertebrates are available for synthetic rutile. A read-across approach between synthetic rutile and TiO2 is used. All reliable acute toxicity tests to invertebrates for TiO2 resulted in unbounded L(E)C50 values ranging from >10 to >10,000 mg TiO2/L, as observed for 4 different invertebrate species in both freshwater and salt water. These reliable results cover a range of TiO2 products with varying particle size (from nano-particles to bulk powders). All these results are taken together in a weight of evidence approach, and it is concluded that TiO2 is not toxic to aquatic invertebrates at >1,000 mg TiO2/L and at >10,000 mg TiO2/L in freshwater and marine water, respectively. The values for synthetic rutile in freshwater and marine water are >1,000 mg TiO2/L and >10,000 mg TiO2/L, respectively.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 1 000 mg/L
Marine water invertebrates
Marine water invertebrates
- Effect concentration:
- 10 000 mg/L
Additional information
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