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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: 215-127-9 | CAS number: 1304-28-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Study not conducted according to existing guidance (1972-study), but test method well described and test conditions well documented. Study meets generally accepted scientific standards
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- Effects of various metals on survival, growth, reproduction and metabolism of Daphnia magna
- Author:
- Biesinger K. E. and Christensen G. M.
- Year:
- 1 972
- Bibliographic source:
- Journal fisheries Research Board of Canada, Vol. 29 No. 12, 1972
- Reference Type:
- secondary source
- Title:
- Barium and Barium Compounds
- Author:
- World Health Organization
- Year:
- 2 001
- Bibliographic source:
- Concise International Chemical Assessment Document 33. World Health Organisation (Geneva)
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- Similar to OECD Guideline 202
- GLP compliance:
- no
Test material
- Reference substance name:
- Barium chloride
- EC Number:
- 233-788-1
- EC Name:
- Barium chloride
- Cas Number:
- 10361-37-2
- IUPAC Name:
- barium dichloride
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test solutions
- Vehicle:
- no
Test organisms
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- Strain: laboratory clone
- Source: University of Michigan
- Age at study initiation (mean and range, SD): 12h +/- 12h
- Feeding during test: no
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 48 h
Test conditions
- Hardness:
- 44 -53 mg/L as CaCO3
- pH:
- 7.4 - 8.2
- Nominal and measured concentrations:
- The number of nominal concentrations tested ranged from 5 to 12 depending on the toxicant and the initial effects observed
- Details on test conditions:
- - No. of organisms per vessel: 10
- No. of vessels per concentration (replicates): 2
Tests were run both with and without food additions. Complete immobilization or death was the endpoint
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: Lake Superior water; unfiltered water strained through a #20 bolting cloth
- Metals: 14 µg Ba/L ; 16 µg Sr/L ; 0.78 µg Zn/L ; <0.5 µg Ni/L ; 1.51 µg Cu/L ; <0.5 µg Co/L ; < 0.01 g Hg/L ; < 0.1 µg Cd/L
- Chloride: 1.22 mg/L
- Alkalinity: 42.3 mg/L as CaCO3
- Ca: 13.7 mg /L
- Mg: 3.12 mg/L
- K: 0.53 mg/L
- Na: 1.13 mg/L
Results and discussion
Effect concentrations
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 14.5 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- element
- Basis for effect:
- mobility
- Remarks:
- and mortality
- Reported statistics and error estimates:
- Results were statistically evaluated with the method of Lichtfield and Wilcoxon (1949) for establishing appoximations of the 95% confidence limit for survival
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.