N-(cyclopent-1-en-1-yl)morpholine

Guidance on Safe Use

First-aid measures

1. Description of first aid measures

General notes

Do not leave affected person unattended. Remove victim out of the danger area. Keep affected person warm, still and covered.

Take off immediately all contaminated clothing. In all cases of doubt, or when symptoms persist, seek medical advice. In case

of unconsciousness place person in the recovery position. Never give anything by mouth.

Following inhalation

If breathing is irregular or stopped, immediately seek medical assistance and start first aid actions. In case of respiratory tract irritation,

consult a physician. Provide fresh air.

Following skin contact

Wash with plenty of soap and water.

Following eye contact

Remove contact lenses, if present and easy to do. Continue rinsing. Irrigate copiously with clean, fresh water for at least 10

minutes, holding the eyelids apart.

Following ingestion

Rinse mouth with water (only if the person is conscious). Do NOT induce vomiting.

2. Most important symptoms and effects, both acute and delayed

Symptoms and effects are not known to date.

3. Indication of any immediate medical attention and special treatment needed

none

Fire-fighting measures

1. Extinguishing media

Suitable extinguishing media

Water spray, Foam, Dry extinguishing powder, Carbon dioxide (CO2)

Unsuitable extinguishing media

Water jet

2. Special hazards arising from the substance or mixture

The exposure of containers to heat leads to an increase in pressure with a risk of bursting and subsequent explosion. Develops

corrosive and irritant vapours. May form explosive mixtures with air at elevated ambient temperatures. May

be corrosive to metals-> Formation of Hydrogen ->may form an explosive mixture with air. The vapours may be invisible and

are heavier than air. They spread on the ground and can intrude into sewers and cellars.

Hazardous combustion products

Carbon monoxide (CO), Carbon dioxide (CO2), Nitrous gases

3. Advice for firefighters

Keep containers cool with water spray. In case of fire and/or explosion do not breathe fumes. Co-ordinate firefighting measures

to the fire surroundings. Do not allow firefighting water to enter drains or water courses. Collect contaminated firefighting water

separately. Fight fire with normal precautions from a reasonable distance. Precipitate combustion gases with water spray if possible.

Wear self-contained breathing apparatus.

Accidental release measures

1. Personal precautions, protective equipment and emergency procedures

For non-emergency personnel

Remove persons to safety.

For emergency responders

Wear breathing apparatus if exposed to vapours/dust/spray/gases.

2. Environmental precautions

Keep away from drains, surface and ground water. Retain contaminated washing water and dispose of it.

3. Methods and material for containment and cleaning up

Advice on how to contain a spill

Covering of drains

Advice on how to clean up a spill

Wipe up with absorbent material (e.g. cloth, fleece). Collect spillage: sawdust, kieselgur (diatomite), sand, universal binder

Appropriate containment techniques

Use of adsorbent materials.

Other information relating to spills and releases

Place in appropriate containers for disposal. Ventilate affected area.

4. Reference to other sections: Hazardous combustion products: see section "Firefighting measures". Personal protective equipment: see section "Exposure controls/personal protection". Incompatible materials: see section "Stability and reactivity". Disposal considerations: see section "Disposal considerations"

Handling and storage

This substance is handled under Strictly Controlled Conditions in accordance with REACH regulation Article 18(4) for transported isolated intermediates. Site documentation to support safe handling arrangements including the selection of engineering, administrative and personal protective equipment controls in accordance with risk-based management systems is available at each Manufacturing site. Written confirmation of application of Strictly Controlled Conditions has been received from affected Distributor and Downstream Manufacturer/User of the Registrant's intermediate.

1. Precautions for safe handling

Recommendations

- measures to prevent fire as well as aerosol and dust generation

Use local and general ventilation. Avoidance of ignition sources. Keep away from sources of ignition - No smoking. Take precautionary

measures against static discharge. Use only in well-ventilated areas. Due to danger of explosion, prevent leakage of

vapours into cellars, flues and ditches. Ground/bond container and receiving equipment. Use explosion-proof electrical/ventilating/

lighting/equipment. Use only non-sparking tools.

- specific notes/details

Places which are not ventilated, e.g. unventilated below ground level areas such as trenches, conduits and shafts, are particularly

prone to the presence of flammable substances or mixtures. Vapours are heavier than air, spread along floors and form explosive

mixtures with air. Vapours may form explosive mixtures with air.

Advice on general occupational hygiene

Wash hands after use. Do not eat, drink and smoke in work areas. Remove contaminated clothing and protective equipment before

entering eating areas. Never keep food or drink in the vicinity of chemicals. Never place chemicals in containers that are

normally used for food or drink. Keep away from food, drink and animal feedingstuffs.

2. Conditions for safe storage, including any incompatibilities

Managing of associated risks

- explosive atmospheres

Keep container tightly closed and in a well-ventilated place. Use local and general ventilation. Keep cool. Protect from sunlight.

- flammability hazards

Keep away from sources of ignition - No smoking. Keep away from heat, hot surfaces, sparks, open flames and other ignition

sources. No smoking. Take precautionary measures against static discharge. Protect from sunlight.

- incompatible substances or mixtures

Protect from moisture.

- ventilation requirements

Use local and general ventilation. Ground/bond container and receiving equipment.

- packaging compatibilities

Only packagings which are approved (e.g. acc. to ADR) may be used.

3. Specific end use(s)

No information available.

Transport information

Shipping

SpecialProvisions

Shipping

Remarks

Marine transport (UN RTDG/IMDG)

Shipping

Remarks

Shipping

Remarks

SpecialProvisions

Exposure controls / personal protection

This substance is handled under Strictly Controlled Conditions in accordance with REACH regulation Article 18(4) for transported isolated intermediates. Site documentation to support safe handling arrangements including the selection of engineering, administrative and personal protective equipment controls in accordance with risk-based management systems is available at each Manufacturing site. Written confirmation of application of Strictly Controlled Conditions has been received from affected Distributor and Downstream Manufacturer/User of the Registrant's intermediate.

1. Control Parameters

Control parameters, national occupational exposure limit values (workplace exposure limits) as well as information on control parameters of possible hydrolysis products, impurities and/or additives hydrolysis products are provided in the safety data sheet.

2. Exposure controls

Appropriate engineering controls

Local and general ventilation.

Individual protection measures (personal protective equipment)

Eye/face protection

Splash goggles.

Skin protection

- hand protection

Wear suitable gloves. Chemical protection gloves are suitable, which are tested according to EN 374. Check leak-tightness/impermeability

prior to use. In the case of wanting to use the gloves again, clean them before taking off and air them well. For special

purposes, it is recommended to check the resistance to chemicals of the protective gloves mentioned above together with

the supplier of these gloves.

- type of material NBR: acrylonitrile-butadiene rubber

- material thickness 0,38 mm (splash protection)

- breakthrough times of the glove material >30 minutes (permeation: level 2) (splash protection)

- other protection measures

For special purposes, it is recommended to check the resistance to chemicals of the protective gloves mentioned above together

with the supplier of these gloves. In the case of wanting to use the gloves again, clean them before taking off and air them

well.

Take recovery periods for skin regeneration. Preventive skin protection (barrier creams/ointments) is recommended. Wash

hands thoroughly after handling. Protective clothing against liquid chemicals. Footwear protecting against chemicals.

Respiratory protection

In case of inadequate ventilation wear respiratory protection.

Environmental exposure controls

Use appropriate container to avoid environmental contamination. Keep away from drains, surface and ground water.

Stability and reactivity

1. Reactivity

Concerning incompatibility: see below "Conditions to avoid" and "Incompatible materials". The mixture contains reactive substance(s). Risk of ignition.

If heated:

Risk of ignition

2. Chemical stability

See below "Conditions to avoid".

3. Possibility of hazardous reactions

Acids, Bases, Oxidiser -> Heat

4. Conditions to avoid

Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. Protect from moisture.

Hints to prevent fire or explosion

Use explosion-proof electrical/ventilating/lighting/equipment. Use only non-sparking tools. Take precautionary measures

against static discharge.

5. Incompatible materials

Acids, Bases, Oxidisers

6. Hazardous decomposition products

Hazardous combustion products: see section "firefighting measures".

Disposal considerations

Waste treatment methods

Waste treatment-relevant information

Dispose of contents/container in accordance with local/regional/national/international regulations.

Sewage disposal-relevant information

Do not empty into drains. Avoid release to the environment. Refer to special instructions/safety data sheets.

Waste treatment of containers/packagings

It is a dangerous waste; only packagings which are approved (e.g. acc. to ADR) may be used. Completely emptied packages

can be recycled. Handle contaminated packages in the same way as the substance itself.

Remarks

Please consider the relevant national or regional provisions. Waste shall be separated into the categories that can be handled

separately by the local or national waste management facilities.