Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 213-034-8 | CAS number: 917-70-4
Toxicity to birds
Administrative data
Link to relevant study record(s)
Description of key information
A single key study (Zohravi, 2006) was used to cover this endpoint. This study yielded 28-d NOECs for both mortality and growth of Japanese quails of >= 44 and >= 57 mg La/kg diet when supplying lanthanum as La(CH3COO)3 or LaCl3, respectively. These values correspond to >= 100 and >= 130 mg lanthanum acetate/kg diet.
Key value for chemical safety assessment
Additional information
A single reliable study was identified on the toxicity of lanthanum to birds. In this study (Zohravi, 2006), one-day old Japanese quails were exposed to La (added as LaCl3 or La(CH3COO)3) for 4 weeks via their diet (two doses). No significant decrease of growth or increase of mortality was observed during the test compared to the control treatment. The NOECs for both mortality and growth were therefore >= 44 mg La/kg diet for the study with lanthanum acetate and >= 57 mg La/kg diet for the study with lanthanum chloride. When expressed as lanthanum acetate, these NOECs correspond to values of >= 100 mg/kg diet and >= 130 mg/kg diet.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
