Registration Dossier
Registration Dossier
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EC number: 209-909-9 | CAS number: 597-82-0
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The inhibition of the degradation activity of activated sludge is not anticipated when introduced in appropriate low concentrations.
Key value for chemical safety assessment
Additional information
Two studies on toxicity to microorganisms are available. In the key study (Ciba-Geigy 1988), sewage sludge micro-organisms were exposed for 3h to the test item at a nominal concentration of 100 mg/L in accordance with OECD 209. The IC50 value based on respiration rate was >100 mg/L. As no effects were observed the NOEC is expected to be at least 100 mg/L.
In a supporting study according to OECD guideline 209 (RCC 1997) with O,O,O- triphenyl thiophosphate in a lower purity of > 25%, respiration of domestic activated sludge was not inhibited at a test item concentration of 320 mg/L (NOEC) after 3h of exposure, the IC50 is > 1000 mg/L.
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