Registration Dossier
Registration Dossier
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EC number: 209-812-1 | CAS number: 593-84-0
pH
Administrative data
- Endpoint:
- pH
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 04/2021
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study with acceptable restrictions
Cross-reference
- Reason / purpose for cross-reference:
- reference to same study
Reference
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2021-03-01 - 2021-04-30
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- GLP compliance:
- no
- Type of method:
- flask method
- Specific details on test material used for the study:
- Lot 2103311210
- Key result
- Water solubility:
- ca. 1 562 g/L
- Conc. based on:
- test mat.
- Incubation duration:
- > 24 - <= 120 h
- Temp.:
- 20 °C
- pH:
- ca. 6.2
- Conclusions:
- The mean watersolubility of Guanidinium thiocyanate is 1562 g/L at 20 +/- 0.5 °C.
The pH of the satureted solution is 6.2. - Executive summary:
The solubility of Guanidinium Thiocyanate was determined in water at a temperature of 20 ± 0.5 °C according to OECD guideline 105 (Shake Flask) with restrictions.
The results are presented in the following table:
Solubility of guanidinium thiocyanate in water at 20 ± 0.5 °CDetermined pH 6.2 Mean solubility [g/L] 1562
The repeated samplings indicate the required reproducibility (relative standard deviation below 15%).
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 021
- Report date:
- 2021
Materials and methods
Test guideline
- Guideline:
- other: OECD 105
- GLP compliance:
- no
Test material
- Reference substance name:
- Guanidinium thiocyanate
- EC Number:
- 209-812-1
- EC Name:
- Guanidinium thiocyanate
- Cas Number:
- 593-84-0
- Molecular formula:
- CH5N3.CHNS
- IUPAC Name:
- amino(imino)methanaminium thiocyanate
- Reference substance name:
- unknown
- IUPAC Name:
- unknown
- Test material form:
- solid: bulk
Constituent 1
impurity 1
- Specific details on test material used for the study:
- Lot2103311210
Results and discussion
pH value
- Key result
- pH value:
- 6.2
- Temp.:
- 20 °C
- Concentration:
- 1 562 g/L
Applicant's summary and conclusion
- Conclusions:
- The pH of a satureted solution of GTC is 6.2
- Executive summary:
In a watersolubility study according to OECD 105 with GTC the pH of the saturated solution was determined.
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