Registration Dossier
Registration Dossier
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EC number: 207-431-5 | CAS number: 470-82-6
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 57 µg/L
- Assessment factor:
- 1 000
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 0.57 mg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 5.7 µg/L
- Assessment factor:
- 10 000
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 10 mg/L
- Assessment factor:
- 10
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 1.425 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 0.142 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 0.25 mg/kg soil dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- PNEC oral
- PNEC value:
- 40 mg/kg food
- Assessment factor:
- 300
Additional information
The PNEC for the aquatic environment are derived from the lowest effect level observed in the available acute aquatic toxicity tests by applying the relevant assessment factors to the lowest L(E)C50 in accordance with ECHA Guidance R.10.
PNECSTP can be calculated via biodegradation studies or ASRI studies where the concentration where no toxicity to microorganisms was observed (can be considered NOEC). An assessment factor of 10 should be used when evaluation PNECSTP in this way.
Wet weight PNECs for sediment and soil were calculated using equilibrium partitioning as described in Guidance R.10 & R.16, conversion to dry weight was performed with factor of 4.6 for sediment and 1.13 for soil.
Using the value 600mg/kg bw/d NOEL from the available reproduction toxicity study, multiplied by a correction factor of 20 for rat > 6 weeks and divided by AF 200 for subchroinc study giving a PNEC of 40 mg/kg.
Conclusion on classification
Based on the results from the aquatic toxicity testing (lowest short-term L(E)C50 is 57mg/l) and since the substance is readily biodegradable, cineole is not classified as hazardous to the aquatic environment according to Directive 67/548/EEC (DSD). Since the logKow < 4, it is also not classified as hazardous to the aquatic environment according to the CLP Regulation 1272/2008/EC & adaptation 286/2011/EC.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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