Registration Dossier
Registration Dossier
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EC number: 205-775-0 | CAS number: 150-84-5
Endpoint summary
Administrative data
Description of key information
Acute toxicity:
- oral: LD50 = 6800 mg/kg bw (Calandra 1971)
- dermal: LD50 >2000 mg/kg bw (Calandra 1971)
Key value for chemical safety assessment
Additional information
Acute oral toxicity:
In the chosen key study for acute oral toxicity, two male and two female Sprague-Dawley rats were dosed with citronellyl acetate at concentrations of 3000, 4600, 6800 and 10200 mg/kg bw (Calandra, 1971). The LD50 has been set at 6800 mg/kg bw.
Acute inhalative toxicity:
No data are available for acute inhalative toxicity of citronellyl acetate. For the coverage of a second and human relevant route of exposure, data on acute dermal toxicity are available. Based on the available acute oral and dermal data, no acute inhalative toxicity for citronellyl acetate is indicated.
Acute dermal toxicity:
In the chosen key study for acute dermal toxicity, two New Zealand White rabbits per sex were treated with undiluted citronellyl acetate at 2000 mg/kg bw under occlusion for 24 hours (Calandra, 1971). No mortalities were observed and a LD 50 of >2000 mg/kg bw has been set.Justification for classification or non-classification
The present data on acute oral and dermal toxicity do not fulfill the criteria laid down in 67/548/EEC and regulation (EU) 1272/2008, and therefore, a non-classification is warranted.
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