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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Description of key information

Only data are available for structural analogue Na3HEDTA, hence read across and molecular weight corrections have been applied.

LC5 (96h): marine species (Scophthalmus maximus) > 738 mg/L. Freshwater species 808 mg/L in Lepomis macrochirus, 372 mg/L in Pimephales promelas and between 862 and 1861 mg/L in Leuciscus idus. For H3HEDTA the lowest LC50 would hence be 276.3/344.2 x 372 = 299 mg/L

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
299 mg/L

Additional information

A number of studies have been done to investigate short term effects on fish of HEDTA, including one study on a marine species (Scophthalmus maximus) (Schlumberger Dowell, 1999) and a number of studies on freshwater species. In the marine species, no mortalities were reported at the maximum exposure concentration of 738 mg/L. Data from the freshwater studies reveal an LC50 of 808 mg/L in Lepomis macrochirus, 372 mg/L in Pimephales promelas and between 862 and 1861 mg/L in Leuciscus idus. These all indicate that acute toxicity to fish is low.