Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 205-575-3 | CAS number: 142-96-1
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
A 96-hr static exposure was conducted with di-n-butyl ether (DnBE) exposed to the green alga Pseudokirchneriella subcapitata. The 72-hr ErC50 for specific growth rate was 19.1 mg DnBE/L and the NOEC was 8.91 mg DnBE/L.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 19.1 mg/L
Additional information
The compound di-n-butyl ether (DnBE) was evaluated for its effects on the growth of the green alga Pseudokirchneriella subcapitata , over a 96-hour static exposure period. The data from this key study were used to determine the 72- and 96-hour ErC50s (based on growth rate), EyC50s (based on cell density), and no-observed-effects concentrations (NOECs) for each endpoint. Based on mean measured concentrations, the 72-hour calculated ErC50 (95% confidence intervals) for specific growth rate was 19.1 (10.1, 28.2) mg DnBE/L and the NOEC was 8.91 mg DnBE/L. A supporting study was also available that reported the toxicity of dibutyl ether (DnBE) to the blue-green algae (cyanobacteria), Microcysis aeruginosa. The 8 day NOEC was >= 50 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
