Registration Dossier
Registration Dossier
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EC number: 204-661-8 | CAS number: 123-91-1
Biodegradation in soil
Administrative data
Link to relevant study record(s)
Description of key information
No simulation tests on the biodegradation of the test substance in soil are deemed necessary.
Key value for chemical safety assessment
Additional information
In accordance with Regulation (EC) No 1907/2006, Annex IX, Section 9.2 and 9.2.1.2, Column 2, the simulation test on ultimate degradation in surface water does not need to be conducted as the chemical safety assessment according to Annex I indicates that there is no need to investigate further the degradation of the substance and its degradation products. The risk characterization ratios (RCRs) of the chemical safety assessment are below 1, indicating that the risks are acceptable. Therefore, no biodegradation studies in surface water will be provided. In addition, due to the results of the available tests on ready biodegradability, 1,4-dioxane is considered as poorly biodegradable. Even after prolonged test duration of 60 days only poor biodegradation was observed. Hence, based on the available data it is concluded that the substance is persistent in the aquatic environment. Moreover, a publication on simulation of in situ biodegradation of 1,4-dioxane under metabolic and cometabolic conditions is available (Barajas-Rodriguez et. all, 2018, 2019). In this publication, using calibrated models, simulations were performed for in situ biodegradation of 1,4-dioxane by metabolism and cometabolism. For both simulations models the times were ranging from 2 and above 40 years.
In addition, 1,4-dioxane has a low potential for adsorption (see IUCLID chapter 5.4.1) and distribution modelling clearly shows the main target for environmental distribution will be water (see IUCLID chapter 5.4.3) indicating a low potential for adsorption to soil. Exposure of soil organisms is, thus, unlikely. Therefore, no further tests on biodegradation in soil are performed.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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