N-(2-ethylhexyl)-8,9,10-trinorborn-5-ene-2,3-dicarboximide

Partition coefficient

Link to relevant study record(s)

Reference

Endpoint:

partition coefficient

Type of information:

experimental study

Adequacy of study:

key study

Study period:

1987

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

comparable to guideline study

Qualifier:

equivalent or similar to guideline

Guideline:

EPA OPPTS 830.7570 (Partition Coefficient, n-octanol / H2O, Estimation by Liquid Chromatography)

Version / remarks:

Guideline D-63-11 was followed as only available guideline at time of report

GLP compliance:

yes

Type of method:

HPLC method

Partition coefficient type:

octanol-water

Type:

log Pow

Partition coefficient:

3.61

Temp.:

24 °C

Remarks on result:

other: isomer I

Type:

log Pow

Partition coefficient:

3.8

Temp.:

24 °C

Remarks on result:

other: isomer II

Key result

Type:

log Pow

Partition coefficient:

ca. 3.71

Temp.:

24 °C

Remarks on result:

other: mean of the two isomers

The equation for standard reference line as determined by linear regression analysis is log P = 5.4080 log (retention time) - 1.1110. The correlation coefficeint was 0.9743.

Result table for standard compounds:

Standard Compound  Retention time (Tr) (min)  Log Tr  Log P  Benzene 4.72  0.674  2.13  Bromobenzene 5.73  0.758  2.99   Biphenyl 7.68  0.885  3.76   Bibenzyl 9.63  0.984  4.81   p,p'-DDE 17.97  1.255  5.69   2,4,5,2',5'-PCB 24.54  1.390  6.11

Conclusions:

Partition coefficient 3.61 and 3.8 for isomer 1 and 2, respectively.
Mean of the two isomers is 3.71

Description of key information

The partition coefficient is 3.61 and 3.8 for isomer 1 and 2, respectively. The mean of two isomers = 3.71 at 24°C

Key value for chemical safety assessment

Log Kow (Log Pow):

3.71

at the temperature of:

24 °C