Registration Dossier
Registration Dossier
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EC number: 203-942-2 | CAS number: 112-17-4
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Hazard for air
Hazard for terrestrial organisms
Hazard for predators
Additional information
Conclusion on classification
In order to determine the classification for hazardous properties related to the aquatic environment, the criteria of the Regulation (EC) No 1272/2008 (CLP) version 2016 in Annex I were accurately followed.
Short-term (acute) aquatic hazard:
For classification, acute toxicity data is available for two trophic levels, which are: aquatic invertebrates (Daphnia) and algae:
Daphnia: EC50 (48h) = 0.298 mg/L
Algae: ErC50 (72h, growth rate) = 0.113 mg/L
The criteria in Table 4.1.0 (a) of Annex I of the CLP Regulation were applied.
The lowest LC50 or EC50 value can be observed for the algae. According to Table 4.1.0 (a) the substance should be classified for acute aquatic hazard, as the ErC50 value for algae is 0.113 mg/L, which is below the cut-off for classification of 1 mg/L. The substance should be classified as Acute (short-term) aquatic toxic 1.
Long-term (chronic) aquatic hazard:
For chronic classification, chronic data is available for one trophic level, algae. As described in Figure 4.1.1 in the CLP regulation (EC No 1272/2008, version 2016), the most stringent outcome of classification according to Table 4.1.0 (b) (i) or (ii) and (iii) should be used.
Table 4.1.0 (b) (i):
The substance is not readily biodegradable, hence Table 4.1.0 (b) (i) applies.
The EC10 (72h, growth rate) for algae is 0.064 mg/L, which is in the range of cut-off values for classification as chronic category 1: ≤ 0.1 mg/L. Therefore, the substance should be classified for chronic aquatic toxicity, category 1.
Table 4.1.0 (b) (iii):
Classification based on available acute data available and environmental fate data:
Daphnia: EC50 (48h) = 0.298 mg/L
Log Kow = 5.6
The substance is not readily biodegradable.
Based on the criteria Table 4.1.0 (b) (iii), the substance should be classified as chronic aquatic toxic, category 1 since the lowest EC50 value is ≤ 1 mg/L and the low Kow value is ≥ 4.
Most stringent classification:
The conclusion of both assessments is that the substance should be classified for chronic aquatic hazard, category 1.
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