Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Water solubility

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
Study initiation date: 29 July 2009 Study completion date:10. November 2009
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Version / remarks:
adopted on 27 July 1995
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Version / remarks:
Directive 92/69/EEC, Official Journal L 383 A 1992
Deviations:
no
GLP compliance:
yes
Type of method:
flask method
Key result
Water solubility:
0.27 g/L
Conc. based on:
test mat.
Loading of aqueous phase:
6.67 g/L
Incubation duration:
>= 24 - <= 72 h
Temp.:
20 °C
pH:
4.2
Remarks on result:
other: samples were shaken at 30°C for 24, 48 and 72 h, respectively, then equilibrated at 20 ± 0.5 °C
Details on results:
The purified water used for the tests had a pH value of 7.06

Preliminary test

The test item was dissolved in the pre-sample with a concentration of approx. 10E-02 g/L (10 µl/L equivalent to 9 mg/L based on density: 0.905 g/cm^3).

Thus the flask method was performed.

Main test, results:

Sample no. Amount of
test item [mg]		 Added volume of water [mL] Shaking time at 30°C [h] Analysed carbon concentration
[mg C/L]		 Concentration of the test item[mg/L]1) pH value2)
1 127 15 24 190 0.28 4.4*
2 124 15 24 186 0.27 4.3*
3 135 15 48 160 0.24 4.2
4 128 15 48 174 0.26 4.2
5 121 15 72 191 0.28 4.2
6 129 15 72 189 0.28 4.2

1) calculated from the carbon concentration of the sample solutions and the carbon content of the pure test item (67.8 %)

2) The purified water used for the tests had a pH value of 7.06.

*) The samples had to be diluted (1 ml sample + 3 ml water) for the pH-determination due to a too small sample volume.

Descriptive statistics for samples one to 6:

- arithmetic mean value: 0.27 g/L

- standard deviation (SD): 0.02 g/L

- relative SD: 5.97%

Water solubility as a function of time:

- n=2 after 24 h at 30 °C: 0.28 g/L;

- n=2 after 48 h at 30 °C: 0.25 g/L

- n=2 after 72 h at 30 °C: 0.28 g/L

The relative standard deviation (repeatability) of the concentrations in all six samples was smaller than 15 % and the three duplicate sets of samples showed no tendency of increasing concentration

values. Thus the test was satisfactory.

Conclusions:
Water Solubility (OECD 105; flask method): 0.27 g/L at 20 °C (pH 4.2)
Executive summary:

The water solubility of the test item was determined according to OECD guideline no. 105 [adopted on 27 July 1995] and EU test method A.6 [Directive 92/69/EEC, Official Journal L 383 A 1992] with the flask method (AQura, 2009).

Water solubility (at 20 °C): 0.27 g/L (pH 4.2)

Description of key information

Water Solubility (OECD 105; flask method): 0.27 g/L at 20 °C (pH 4.2)

Key value for chemical safety assessment

Water solubility:
0.27 g/L
at the temperature of:
20 °C

Additional information

The water solubility of the test item was determined according to OECD guideline no. 105 [adopted on 27 July 1995] and EU test method A.6 [Directive 92/69/EEC, Official Journal L 383 A 1992] with the flask method (AQura, 2009).

Water solubility (at 20 °C): 0.27 g/L (pH 4.2)