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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Key value for chemical safety assessment

Additional information

The results of this study indicate there was no substance-related toxicological effects of adiponitrile

Short description of key information:

1. In-vitro microbial mutagenicity: negative

2. In-vitro mouse lymphoma assay: negative

3. In vitro UDS test: negative

4. In-vivo bone marrow chromosome test: negative

Endpoint Conclusion: No adverse effect observed (negative)

Justification for classification or non-classification

Adiponitrile did not exhibit mutagenic or clastogenic effects in either in vivo or in vitro tests systems. Therefore, adiponitrile is not considered a mutagen under GHS or DSD classification criteria.