Registration Dossier
Registration Dossier
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EC number: 203-816-7 | CAS number: 110-93-0
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Remarks:
- under GLP, validity criteria met
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- GLP compliance:
- yes
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic (adaptation not specified)
- Duration of test (contact time):
- 28 d
- Initial conc.:
- 85 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- TEST SYSTEM- Test mixture containing 85 mg/L test substance, anorganic medium and 10mL non-adapted activated sludge from a laboratory wastewater treatment plant treating municipal wastewater were incubated for 28 days in a respirometer- The BOD for each treatment including the controls were measured daily and compared to the ThOD- Replicates: for statistical reasons seven replicates were prepared.
- Reference substance:
- aniline
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- ca. 91
- Sampling time:
- 28 d
- Details on results:
- The adaptation phase was approximately 4 days. Within the 10-day window the substance was biodegraded for >60 % which indicates ready biodegradation.Kinetic of test substance (in %): < 10 after 4 day(s)= 74 after 14 day(s)ca. 91 after 25 day(s)
- Results with reference substance:
- The biodegradation of the control substance aniline was 85 % within 28 days. Kinetic of control substance (in %): = 85 after 28 day(s)
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
Reference
Description of key information
Biodegradability of the test substance was investigated in a OECD301F guideline study under GLP. Test substance concentration was 85 mg/L and sludge used was from a sewage treatment plant treating domestic waste water. The substance was readily biodegradable, based on 91% degradation in 28 d, meeting the 10d window.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
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