Registration Dossier
Registration Dossier
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EC number: 203-745-1 | CAS number: 110-19-0
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
A TTC (16h) (equivalent to an EC3-value) of 200 mg/L was measured for growth inhibition effects on Pseudomonas putida (Bringmann & Kühn, 1976).
Key value for chemical safety assessment
- EC10 or NOEC for microorganisms:
- 200 mg/L
Additional information
The effect of isobutyl acetate on Pseudomonas putida was tested in a growth inhibition test with a duration of 16 h. In this static freshwater test a toxicity threshold concentration (TTC), equivalent to an EC3, of 200 mg/L was observed (Bringmann & Kühn, 1976).
This result is supported by two other studies (Hüls, 1988 and Krebs, 1992):
The toxicity of isobutyl acetate to microorganisms was investigated in an oxygen consumption test that was conducted according to a German national guideline (DIN 38 412 - L 27) using Pseudomonas putida. The EC10-value (487 mg/L) and the EC50-value (1886 mg/L) do not indicate substantial toxicity to microorganisms (Hüls, 1988).
The effect of isobutyl acetate was tested in a 24 -h depletion test with heterotrophic bacteria (non-adapted). The resulting EC10 (24 h) was > 1000 mg/L (Krebs, 1991).
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