Registration Dossier
Registration Dossier
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EC number: 203-539-1 | CAS number: 107-98-2
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
A GLP guideline study according to ASTM guideline is available for propylene glycol methyl ether. This study is supported by a non-GLP study according to EU method C.2 and a GLP-study equivalent to OECD guideline 202.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 23 300 mg/L
Additional information
In the key study daphnia were exposed to concentrations ranging from 1,412 to 50,000 mg/l. Based on these nominal concentrations, the 48-hour EC50 was determined to be 23,300 mg/l.
In the two supporting studies, daphnia were exposed to concentrations ranging from 62.5 to 500 mg/l and to 1,000 mg/l. Based on these nominal concentrations, the 48-hour EC50 were determined to be superior to 500 mg/l and superior to 1,000 mg/l, respectively, since no immobility was found during the test.
The 48-hour EC50 of 23,300 mg/l will be taken into account for the risk assessment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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