Registration Dossier
Registration Dossier
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EC number: 203-457-6 | CAS number: 107-05-1
Short-term toxicity to fish
Administrative data
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: The study was performed following principles which to a large extent are similar to those of OECD Guideline No 204. The results thus are considered as reliable with restrictions.
Data source
Reference
- Reference Type:
- publication
- Title:
- Quantitative correlation studies between the acute lethal toxicity of 15 organic halides to the guppy (Poecillah Reticulata) and chemical reactivity towards 4-nitrobenzylpyridine
- Author:
- Hermens J, Busser F, Leeuwanch P and Musch A
- Year:
- 1 985
- Bibliographic source:
- Toxicology and Environmental Chemistry 9(3), 219-236
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 204 (Fish, Prolonged Toxicity Test: 14-day Study)
- GLP compliance:
- no
Test material
- Reference substance name:
- 3-chloropropene
- EC Number:
- 203-457-6
- EC Name:
- 3-chloropropene
- Cas Number:
- 107-05-1
- Molecular formula:
- C3H5Cl
- IUPAC Name:
- 3-chloroprop-1-ene
- Details on test material:
- Purity >99 %
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test solutions
- Vehicle:
- no
- Details on test solutions:
- The test solutions were renewed every 24 hours.
Test organisms
- Test organisms (species):
- Poecilia reticulata
- Details on test organisms:
- no details
Study design
- Test type:
- semi-static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 14 h
Test conditions
- Hardness:
- no data
- Test temperature:
- no data
- pH:
- no data
- Dissolved oxygen:
- no data
- Salinity:
- no data
- Nominal and measured concentrations:
- no data
Results and discussion
Effect concentrations
- Duration:
- 14 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 1.2 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Conclusions:
- A prolonged 14-day toxicity test with 3-chloropropene in Poecilia reticulata resulted in a LC50 value of 1.2 mg/.
- Executive summary:
The prolonged toxicity of 3-chloropropene to Poecilia reticulata was tested in a 14-day semi-static toxicity study following principles equivalent to those laid down in OECD Guideline No 204 with restrictions. The test solutions were renewed every 24 hours. No analytical determination of concentrations was performed. The LC50 value found in the study was 1.2 mg/L.
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