Registration Dossier
Registration Dossier
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EC number: 203-378-7 | CAS number: 106-25-2
Melting point / freezing point
Administrative data
Link to relevant study record(s)
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- September 2011
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study with acceptable restrictions
- Remarks:
- This study was considered as reliable with restrictions because it was not conducted under GLP and there are some lack of details in the study report.
- Reason / purpose for cross-reference:
- reference to other study
- Reason / purpose for cross-reference:
- reference to same study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 102 (Melting point / Melting Range)
- Deviations:
- not specified
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.1 (Melting / Freezing Temperature)
- Deviations:
- not specified
- GLP compliance:
- no
- Type of method:
- method to determine freezing temperature
- Key result
- Melting / freezing pt.:
- < -20 °C
- Atm. press.:
- ca. 1 atm
- Decomposition:
- no
- Sublimation:
- no
- Conclusions:
- No freezing point or range could be detected.
The freezing point of nerol was stated as < - 20°C. - Executive summary:
The determination of the melting point was performed in accordance with Regulation (EC) No 440/2008, method A.1 “Melting/Freezing Temperature” (May 2008) and OECD Guideline No 102 “Melting Point/Melting Range” (July 1995).
In a preliminary study, the test item was still not frozen after twelve hours of storage in a freezer at - 20°C; according to Annex VII of REACH, no main study was performed. The freezing point or range of nerol was stated as < - 20°C.
No observations were made which might cause doubts on the validity of the study outcome. Therefore, the result of the study is considered valid.
Reference
After twelve hours of storage in a freezer at - 20°C the test item was still liquid.
According to Annex VII of REACH, the study does not need to be conducted below a lower limit of - 20°C. Therefore no main study was performed and the determination was terminated.
Description of key information
In a preliminary study, the test item was still not frozen after twelve hours of storage in a freezer at - 20°C.
Therefore, according to Annex VII of REACH,
no main study was performed.
The freezing point or range of nerol is < - 20°C.
Key value for chemical safety assessment
- Melting / freezing point at 101 325 Pa:
- -20 °C
Additional information
Key study conducted according to OECD 102 and EU A.1 guidelines. The result is scientifically acceptable but not obtained under GLP.
Therefore a reliability of 2 (reliable with restrictions) was assigned.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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