Bis(2-ethylhexyl)amine

Ecotoxicological Summary

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:

PNEC aqua (freshwater)

PNEC value:

0.001 mg/L

Assessment factor:

50

Extrapolation method:

assessment factor

PNEC freshwater (intermittent releases):

0.015 mg/L

Marine water

Hazard assessment conclusion:

PNEC aqua (marine water)

PNEC value:

0 mg/L

Assessment factor:

500

Extrapolation method:

assessment factor

STP

Hazard assessment conclusion:

PNEC STP

PNEC value:

1.8 mg/L

Assessment factor:

10

Extrapolation method:

assessment factor

Sediment (freshwater)

Hazard assessment conclusion:

PNEC sediment (freshwater)

PNEC value:

43.6 mg/kg sediment dw

Extrapolation method:

equilibrium partitioning method

Sediment (marine water)

Hazard assessment conclusion:

PNEC sediment (marine water)

PNEC value:

4.36 mg/kg sediment dw

Extrapolation method:

equilibrium partitioning method

Hazard for air

Air

Hazard assessment conclusion:

no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:

PNEC soil

PNEC value:

0.2 mg/kg soil dw

Assessment factor:

100

Extrapolation method:

assessment factor

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:

no potential to cause toxic effects if accumulated (in higher organisms) via the food chain

Conclusion on classification

Official classification regarding environmental hazards:

 

Aquatic compartment

 

In accordance with Regulation (EC) No 1272/2008, Annex VI Table 3.1 or Table 3.2: no data found

 

Self-classification:

 

The self-classification based on the following data:

 

- Acute effect values:

Acute fish: LC50 (96 h) >1.5 - < 2.2 mg/L; acute D. magna: EC50 (48 h) 2.2 mg/L; algae: ErC50 (72 h) 1.55 mg/L

 

- Chronic effect values:

Long-term D. magna: 21-d NOEC (reproduction, growth) = 0.069 mg/L; algae: ErC10 (72 h) 0.14 mg/L

 

- Biodegradation:

The biodegradability of the chemical was assessed in a weight-of evidence approach including experimental and estimated data on the biodegradability of the substance. The substance is concluded to be readily biodegradable, but failing the 10 -day window (according to OECD criteria)

According to the GHS a chemical may be considered as rapidly biodegradable in case of "other convincing scientific evidence is available to demonstrate that the substance can be degraded in the aquatic environment to a level >70% within 28d". In the OECD 301B study (BASF SE, 2016) two out of three replicates exceeded the threshold value of 70% within 28 days. However, the TSmean was 69% CO2/ThCO2 after 28d.

- log Pow:

Log Pow 7.3 at 25 °C and pH 7.5

 

Following GHS, the substance is not to be classified as acutely hazardous to the aquatic environment.

 

Rationale:

The substance is not to be classified as acutely hazardous to the aquatic environment, since the lowest acute effect values are greater than 1 mg/L.

 

Following GHS, the substance is to be classified as chronically hazardous to the aquatic environment (Category Chronic 1).

 

Rationale:

Chronic data are available for algae and Daphnia. Therefore classification is based on the available chronic and acute toxicity data.

- Chronic toxicity data: The substance is not rapidly degradable and the NOEC is 0.069 mg/L. According to the criteria outlined in Table 4.1.0(b) (i) (Commission Regulation (EU) No 286/2011 amending Regulation (EC) No 1272/2008) the substance is to be classified as chronically hazardous to the aquatic environment (Category chronic 1).

- Acute toxicity data: Fish is the trophic level not covered by chronic data. Therefore classification is based on the respective acute effect data. The LC50 is between 1.5 and 2.2 mg/L, the substance is not rapidly degradable (readily biodegradable, but failing 10-day window) and the log Pow is > 4. According to the criteria outlined in Table 4.1.0(b) (iii) (Commission Regulation (EU) No 286/2011 amending Regulation (EC) No 1272/2008) the substance is to be classified as chronically hazardous to the aquatic environment (Category chronic 2).

- Conclusion: based on chronic toxicity data the substance is to be classified as chronically hazardous to the aquatic environment (Category Chronic 1).

 

According to Table 4.1.3, the M-factor for mixtures is 1.

 

Atmospheric compartment

 

The test substance is not in Annex I of Regulation (EC) 2037/2000 on substances that deplete the ozone layer.

 

The test substance does not belong to the greenhouse gases listed in P Forster, PV Ramaswamy et al. Changes in Atmospheric Constituents and in Radiative Forcing. In: Climate Change 2007: The Physical Basis. Contribution of Working Group I to the Fourth Assessment Report of the Intergovernmental Panel on Climate Change.