Registration Dossier
Registration Dossier
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EC number: 202-863-0 | CAS number: 100-54-9
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Data was not generated using guideline protocols or organisms, but the study is scientifically valid from a reputable laboratory
Data source
Reference
- Reference Type:
- publication
- Title:
- Structure-activity relationships of selected pyridines. III Log Kow analysis
- Author:
- Schultz T et.al
- Year:
- 1 987
- Bibliographic source:
- Ecotoxicol Environ Safety 13:76
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Survival of organism in assays after exposure to test material.
- GLP compliance:
- no
Test material
- Reference substance name:
- Nicotinonitrile
- EC Number:
- 202-863-0
- EC Name:
- Nicotinonitrile
- Cas Number:
- 100-54-9
- Molecular formula:
- C6H4N2
- IUPAC Name:
- pyridine-3-carbonitrile
- Reference substance name:
- Pyridine-3-carbonitrile
- IUPAC Name:
- Pyridine-3-carbonitrile
Constituent 1
Constituent 2
Test organisms
- Test organisms (species):
- other: Tetrahymena pyriformis
Results and discussion
Effect concentrations
- Duration:
- 2.5 d
- Dose descriptor:
- EC50
- Effect conc.:
- 581.6 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: growth
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not applicable
- Remarks:
- not a guideline study
- Conclusions:
- 3-Cyanopyridine has an EC50 for Tetrahymena pyriformis of 581.6 mg/L.
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