Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 202-784-1 | CAS number: 99-75-2
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
In a reliable test (reliability category 1) for acute fish toxicity of methyl-p-toluate using Danio rerio the following effect concentrations were determined:
LC0 (96h): 12.5 mg/L (nominal)
LC50 (96h): 20.5 mg/L (nominal)
LC100 (96h): 50 mg/L (nominal)
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 20.5 mg/L
Additional information
In a reliable test (reliability category 1) for acute fish toxicity of methyl-p-toluate using Danio rerio the following effect concentrations were determined:
LC0 (96h): 12.5 mg/L (nominal)
LC50 (96h): 20.5 mg/L (nominal)
LC100 (96h): 50 mg/L (nominal)
Alterations of appearance and behaviour were observed between 12.5 and 100 mg/L in a dose dependent manner. Alterations of appearance and behaviour observed at 10 mg/L reversed after 72 hours and fish were without symptoms afterwards. No effects were observed at 1 mg/L.
In a non-reliable study (short exposure time, insufficient documentation), the fish LC50 for methyl-p-toluate was determined in a 24 hour exposure study using Oryzias latipes (10 fish per concentration group, vehicle: DMSO). Based on nominal concentrations, the LC50 (24h) was determined as 78.8 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
