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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:
PNEC aqua (freshwater)
PNEC value:
0.194 mg/L
Assessment factor:
50
Extrapolation method:
assessment factor
PNEC freshwater (intermittent releases):
0.18 mg/L

Marine water

Hazard assessment conclusion:
PNEC aqua (marine water)
PNEC value:
0.019 mg/L
Assessment factor:
500
Extrapolation method:
assessment factor

STP

Hazard assessment conclusion:
PNEC STP
PNEC value:
54.3 mg/L
Assessment factor:
10
Extrapolation method:
assessment factor

Sediment (freshwater)

Hazard assessment conclusion:
no hazard identified

Sediment (marine water)

Hazard assessment conclusion:
no hazard identified

Hazard for air

Air

Hazard assessment conclusion:
no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:
no hazard identified

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:
no potential for bioaccumulation

Additional information

Conclusion on classification

Reliable and GLP-conform acute toxicity studies of m-toluic acid are available for algae, daphnids, and fish. Algae appear to be most sensitive with a 72-h EC50 of 18 mg/L. Thus, all effect concentrations are well above the classification cut-off value for acute (short-term) aquatic hazard category 1. Therefore, m-toluic acid does not meet classification criteria as short-term hazard to the aquatic environment under Regulation (EC) No 1272/2008 and its subsequent adaptations.

 

Regarding chronic toxicity, reliable and GLP-conform studies are available for algae and daphnids; the lowest effect concentration is the 21-d NOEC of 9.7 mg/L for the reproduction of daphnids. According to the QSAR-based outcome of the model ECOSAR v.2.0, m-toluic acid has a very low potential for chronic toxicity to freshwater and saltwater fish with chronic values (ChV = 10^([log (LOEC x NOEC)]/2)) for freshwater and saltwater fish of 47.9 mg/L and 82.9 mg/L, respectively. Thus, effect concentrations and QSAR-based estimates are well above the classification cut-off values for long-term aquatic hazard category 1 -3. Criteria for the "Safety net" classification in Category Chronic 4 are also not met. m-Toluic acid is rapidly biodegradable and the log Kow is well below 4. Therefore, m-toluic acid does not meet classification criteria as long-term hazard to the aquatic environment under Regulation (EC) No 1272/2008.