Registration Dossier
Registration Dossier
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EC number: 202-551-4 | CAS number: 97-00-7
Long-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- long-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: conforms to guideline & GLP
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 994
- Report date:
- 1994
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: OECD 202. Part 2 - effects on biotic systems. 14-d reproduction test
- Deviations:
- yes
- Remarks:
- modificated to 21 days
- GLP compliance:
- yes (incl. QA statement)
Test material
- Reference substance name:
- 1-chloro-2,4-dinitrobenzene
- EC Number:
- 202-551-4
- EC Name:
- 1-chloro-2,4-dinitrobenzene
- Cas Number:
- 97-00-7
- Molecular formula:
- C6H3ClN2O4
- IUPAC Name:
- 1-chloro-2,4-dinitrobenzene
- Details on test material:
- Analytical purity: 99.7 %
Constituent 1
Sampling and analysis
- Analytical monitoring:
- yes
- Details on sampling:
- water samples taken from the beginning and the end in 3 intervals
Test organisms
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- Clone 5 (IRChA, France):
Study design
- Test type:
- semi-static
- Water media type:
- freshwater
- Total exposure duration:
- 21 d
Test conditions
- Test temperature:
- 20.5 - 21.5 ºC
- pH:
- 8.1 - 8.4
- Dissolved oxygen:
- 8.1 - 9.0 mg/l
- Details on test conditions:
- Test concentrations: 0 / 0.01 / 0.032 / 0.1 / 0.32 / 1 mg/l (10 animals used per concentration and control group)
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 21 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 0.32 mg/L
- Basis for effect:
- immobilisation
- Duration:
- 21 d
- Dose descriptor:
- LOEC
- Effect conc.:
- 1 mg/L
- Basis for effect:
- immobilisation
- Duration:
- 21 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 0.1 mg/L
- Basis for effect:
- reproduction
- Duration:
- 21 d
- Dose descriptor:
- LOEC
- Effect conc.:
- 0.32 mg/L
- Basis for effect:
- reproduction
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
