2-sec-butylphenol

Adsorption / desorption

Link to relevant study record(s)

Reference

Endpoint:

adsorption / desorption: screening

Type of information:

experimental study

Adequacy of study:

key study

Study period:

02 Mar 2016 to 23 Jun 2016

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 121 (Estimation of the Adsorption Coefficient (Koc) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC))

GLP compliance:

yes

Type of method:

HPLC estimation method

Media:

other: A moderately polar stationary phase based on a silica matrix was used (EC 150/4.6 Nucleodur 100-5 CN-RP, 5 micrometers

Specific details on test material used for the study:

SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: Supplied by Registrant (SI Group), batch A00000035
- Expiration date of the lot/batch: 28 Jan 2017
- Purity test date:99.6 % w/w

STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: Ambient conditions (5°C to -30°C), dry
- Stability under test conditions: No data.
- Solubility and stability of the test substance in the solvent/vehicle: No data
- Reactivity of the test substance with the solvent/vehicle of the cell culture medium: no data

Test temperature:

According to OECD 121. The analysis was performed on an analytical column packed with a commercially available cyanopropyl solid phase containing lipophilic and polar moieties. A moderately stationary phase based on a silica matrix was used (EC 150/4 Nucleodur 100-5 CN-RP 150 x 4.5 mm; 5 micrometers). A 45/55 ultra-pure water/methanol was used as mobile phase. the column temperature was 25°C +/- 1°C.

Details on study design: HPLC method:

The analysis was performed on an analytical column packed with a commercially available cyanopropyl solid phase containing lipophilic and polar moieties. A moderately stationary phase based on a silica matrix was used (EC 150/4 Nucleodur 100-5 CN-RP 150 x 4.5 mm; 5 micrometers). A 45/55 ultra-pure water/methanol was used as mobile phase. The column temperature was 25°C +/- 1°C.

Details on sampling:

Not applicable, since OECD 121 method.

Details on matrix:

Not applicable, since OECD 121 method.

Details on test conditions:

The analysis was performed on an analytical column packed with a commercially available cyanopropyl solid phase containing lipophilic and polar moieties. A moderately stationary phase based on a silica matrix was used (EC 150/4 Nucleodur 100-5 CN-RP 150 x 4.5 mm; 5 micrometers). A 45/55 ultra-pure water/methanol was used as mobile phase. The column temperature was 25°C +/- 1°C.

Key result

Type:

log Koc

Value:

2.34 dimensionless

Temp.:

25 °C

Matrix:

NA

Remarks on result:

other: HPLC screening method OECD 121 was used.

Details on results (HPLC method):

The mean log KOC was determined to be 2.34.

Validity criteria fulfilled:

yes

Conclusions:

The mean log KOC was determined to be 2.34.

Executive summary:

The sorption characteristics of the substance was investigated under GLP according to OECD 121 (HPLC estimation method). The analysis was performed on an analytical column packed with a commercially available cyanopropyl solid phase containing lipophilic and polar moieties. A moderately stationary phase based on a silica matrix was used (EC 150/4 Nucleodur 100-5 CN-RP 150 x 4.5 mm; 5 micrometers). A 45/55 ultra-pure water/methanol was used as mobile phase. The column temperature was 25°C +/- 1°C. The mean log KOC was determined to be 2.34 (average of 2.34 and 2.33). According to FAO Mobility Classification, the substance is moderately mobile, i.e. it adsorbs moderately.

Description of key information

The mean log KOC was determined to be 2.34 (average of 2.34 and 2.33). According to FAO Mobility Classification, the substance is moderately mobile, i.e. it adsorbs moderately.