Registration Dossier
Registration Dossier
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EC number: 201-089-0 | CAS number: 78-16-0
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
No toxic effects to fish up to the limit of water solubility (< 0.05 mg/L).
Key value for chemical safety assessment
Additional information
The acute toxicity of
2-ethyl-2-[[(1-oxoheptyl)oxy]methyl]propane-1,3-diyl bisheptanoate (CAS
78-16-0) to fish was investigated in a study following OECD guideline
203. Rainbow trout (Oncorhynchus mykiss, reported as Salmo gairdneri)
were used as test organisms (Comber, 1991). The fish were exposed to the
test substance in a semi-static test system. The study was conducted as
a limit test with an exposure time of 96 hours. At test termination a
LC50 >1000 mg/L based on nominal test substance concentrations was
determined.
Thus toxic effects on fish are not expected up to the water solubility
limit of the substance (< 0.05 mg/L).As it can be seen
in the data matrix of the category justification in section 13 and the
overall endpoint summary, IUCLID 6.1, all reliable data in the category
support the hazard assessment of each category member by showing a
consistent pattern of results within the polyol esters category, i.e. no
toxic effects to aquatic organisms were observed up to the limit of
water solubility.
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