Registration Dossier
Registration Dossier
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EC number: 200-877-1 | CAS number: 75-54-7
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
A 72-hour EC50 value of >118 mg/L and a NOEC of ≥118 mg/L have been determined for the effects of a read-across substance (Dimethylsilanediol; CAS No. 1066-42-8) on growth rate of Pseudokirchnerella subcapitata.
Key value for chemical safety assessment
Additional information
No data for toxicity to aquatic algae and cyanobacteria are available for dichloro(methyl)silane. However a study of toxicity to aquatic algae is available for the related substance dimethylsilanediol. Dimethylsilanediol, 1066-42-8, is a close structural analogue of Methylsilanediol, which is the hydrolysis product of Dichloro(methyl)silane, 75-54-7. The hydrolysis half-life of dichloro(methyl)silane indicates that, under conditions relevant to the algal toxicity test, hydrolysis to methylsilanediol and hydrogen chloride will occur. The properties of hydrogen chloride are well characterised and are discussed in the CSR. Its effects on aquatic organisms are limited to those that result from changes to pH in unbuffered media. Read-across between dimethylsilanediol and methylsilandiol is appropriate because both are small molecule alkylsilanols containing Me-Si and HO-Si groups; their properties are expected to be similar.
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