Registration Dossier
Registration Dossier
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EC number: 200-675-3 | CAS number: 68-04-2
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
(r-a) LC50 (48 h) 590 mg/L Leuciscus idus melanotus
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 590 mg/L
Additional information
Some reliable toxicity to freshwater fish data are available for trisodium citrate 68-04-2, however the data are not conclusive, since the reported LC50s are greater than values (>10 mg/L). A reliable fish short term toxicity study is, however, available for the parent acid of trisodium citrate, citric acid 77-92-9. It is considered appropriate to read across the short term toxicity to fish results for trisodium citrate 68-04-2 because under conditions relevant to ecotoxicity assessment, the sodium salt and citric acid are expected to be fully dissociated. Sodium is not expected contribute to the toxicity of the substance being a ubiquitous element.
The test reported (48 h) LC50 values corresponding to 440 mg/L and 760 mg/L determined in two laboratories conducting tests in parallel for the effects of citric acid, CAS 77 -92 -9 on mortality of the freshwater fish Leuciscus idus melanotus.
Calculations of the LC50 for trisodium citrate:
The lowest (48 h) LC50 for citric acid is 440 mg/L, which is equivalent to 440 * 1.34 = 590 mg/L of trisodium citrate
(using MW(trisodium citrate)/MW(citric acid) = 258.1/192.9 = 1.34)
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