Registration Dossier
Registration Dossier
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EC number: 200-262-8 | CAS number: 56-23-5
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Short-term toxicity to aquatic invertebrates: EC50(48h) = 35 mg/L for daphnids, acute toxicity, static (OECD TG 202).
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 35 mg/L
Additional information
There is no fully reliable study of acute toxicity of CTC on daphnia available. There is a weight of evidence that the EC50-48h must be in the range 10 to 100 mg/L, based on the studies published by Bazin et al., 1987: EC50-24h = 97 mg/L, Knie et al, 1983: LC50 -24h = 28 mg/L and LeBlanc, 1980: EC50-48h = 35 mg/L. The data published by Japanese MoE (EC50-48h = 8.1 mg/L) seems to be an outlier, specially when we consider the fully reliable chronic toxicity study (Thompson, 1997) where it was observed no mortality among parent animals, during 21 days up to the highest tested concentration: 5.7 mg/L (measured).
Consequently, we will use the value from LeBlanc as key value for acute toxicity to invertebrates.
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