Information from the Existing Substances Regulation (ESR)

Before REACH entered into force, chemicals were regulated by a number of different regulations and directives. The Council Regulation (EEC) No 793/93 -- also known as the Existing Substances Regulation (ESR) -- was one of these. It introduced a comprehensive framework for the evaluation and control of "existing substances" (substances on the market before 1982). 

The ESR stated that the Commission, in consultation with the Member States, would regularly draw up lists of priority substances which require immediate attention because of their potential effects to human health or the environment. Between 1994 and 2007 (the entry into force of REACH), four such priority lists were published, with a total of 141 substances.

The table gives a complete overview on the risk assessments performed by the Member States for each of the 141 substances listed in the four priority lists.
 
2-methoxy-2-methylbutane 213-611-4 994-05-8 4
Nitrobenzene 202-716-0 98-95-3 3
Cumene 202-704-5 98-82-8 1
4-tert-butylbenzoic acid 202-696-3 98-73-7 4
p-tert-butylphenol 202-679-0 98-54-4 4
2-furaldehyde 202-627-7 98-01-1 2
4-methyl-m-phenylenediamine (toluene-2,4-diamine) 202-453-1 95-80-7 1
3,4-dichloroaniline 202-448-4 95-76-1 1
N-cyclohexylbenzothiazole- 2-sulphenamide 202-411-2 95-33-0 2
Naphthalene 202-049-5 91-20-3 1
2-Methoxyaniline,o-Anisidine 201-963-1 90-04-0 2
2-nitrotoluene 201-853-3 88-72-2 4
1-vinyl-2-pyrrolidone 201-800-4 88-12-0 2
Alkanes, C14-17, chloro (MCCP, Medium chained chlorinated paraffins) 287-477-0 85535-85-9 3
Alkanes, C10-13, chloro (Short Chain Chlorinated Paraffins) 287-476-5 85535-84-8 1
Benzyl butyl phthalate (BBP) 201-622-7 85-68-7 3
Phenol, 4-nonyl-, branched 284-325-5 84852-15-3 2
Dibutyl phthalate 201-557-4 84-74-2 1
5-tert-butyl-2,4,6-trinitro-m-xylene (Musk xylene) 201-329-4 81-15-2 3
4-tert-butyl-2,6-dimethyl-3,5-dinitroacetophenone 201-328-9 81-14-1 3
Methyl methacrylate 201-297-1 80-62-6 1
Bisphenol A,4,4'-isopropylidenediphenol 201-245-8 80-05-7 3
2,2,6,6-tetrabromo-4,4-isopropylidenediphenol 201-236-9 79-94-7 4
Part I
Part II
Methacrylic acid 201-204-4 79-41-4 1
Methyl acetate 201-185-2 79-20-9 1
Chloroacetic acid 201-178-4 79-11-8 3
Acrylic acid 201-177-9 79-10-7 1
Acrylamide 201-173-7 79-06-1 1
Trichloroethylene 201-167-4 79-01-6 1
Calcium fluoride 232-188-7 7789-75-5 4
Sodium dichromate 234-190-3
7789-12-0
10588-01-9
3
Ammonium dichromate 232-143-1 7789-09-5 3
Nickel sulphate 232-104-9 7786-81-4 3
Aluminium fluoride 232-051-1 7784-18-1 4
Chlorine 231-959-5 7782-50-5 3
Trizinc bis(orthophosphate) 231-944-3 7779-90-0 2
Potassium dichromate 231-906-6 7778-50-9 3
Sodium chromate 231-889-5 7775-11-3 3
Zinc sulphate 231-793-3 7733-02-0 2
Hydrogen peroxide 231-765-0 7722-84-1 2
Nickel dichloride 231-743-0 7718-54-9 4
Dimethyl sulphate 201-058-1 77-78-1 2
Hexachlorocyclopentadiene 201-029-3 77-47-4 4
Sodium hypochlorite 231-668-3 7681-52-9 2
Hydrogen fluoride 231-634-8 7664-39-3 1
Zinc chloride 231-592-0 7646-85-7 2
TBHP (Hydroperoxide, 1,1-Dimethylethyl) 200-915-7 75-91-2 3
Methyloxirane (Propylene oxide) 200-879-2 75-56-9 2
Chlorodifluoromethane 200-871-9 75-45-6 2
Acetonitrile 200-835-2 75-05-8 1
Zinc 231-175-3 7440-66-6 2
Cadmium 231-152-8 7440-43-9 3
Nickel 231-111-4 7440-02-0 3
Benzene 200-753-7 71-43-2 1
Propan-1-ol 200-746-9 71-23-8 2
1,2-Benzenedicarboxylic acid, di-C9-11-branched alkyl esters, C10-rich 271-091-4 68515-49-1 2
1,2-Benzenedicarboxylic acid, di-C8-10-branched alkyl esters, C9-rich 271-090-9 68515-48-0 2
Benzene, C10-13-alkyl derivs 267-051-0 67774-74-7 1
Chloroform 200-663-8 67-66-3 2
Pitch, coal tar, high temp. 266-028-2 65996-93-2 3
Distillates (coal tar) 266-027-7 65996-92-1 1
Tetrasodium ethylenediaminetetraacetate 200-573-9 64-02-8 1
Aniline 200-539-3 62-53-3 1
Amines, tallow alkyl 263-125-1 61790-33-8 2
Amines, coco alkyl 262-977-1 61788-46-3 4
Amines, hydrogenated tallow alkyl 262-976-6 61788-45-2 4
Edetic acid 200-449-4 60-00-4 1
Zinc distearate, Fatty acids, C16-18, zinc salts
209-151-9
293-049-4
557-05-1
91051-01-3
2
Trisodium nitrilotriacetate 225-768-6 5064-31-3 3
V6 (2,2-bis(chloromethyl) trimethylene bis[bis(2-chloroethyl)phosphate]) 253-760-2 38051-10-4 4
Nickel carbonate 222-068-2 3333-67-3 4
(3-chloro-2-hydroxypropyl) 222-048-3 3327-22-8 3
Diphenyl ether, octabromo derivative 251-087-9 32536-52-0 1
Diphenyl ether, pentabromo derivative 251-084-2 32534-81-9 2
Pentanol 250-378-8 30899-19-5 3
2,3-epoxypropyltrimethylammonium chloride 221-221-0 3033-77-0 3
Di-isononyl phthalate 249-079-5 28553-12-0 2
Di-isodecyl phthalate 247-977-1 26761-40-0 2
Tris(nonylphenyl) phosphite (TNPP) 247-759-6 26523-78-4 4
Methylenediphenyl diisocyanate 247-714-0 26447-40-5 3
Hexabromocyclododecane (HBCDD) 247-148-4 25637-99-4 2
Reaction mass of 2,4,4-Trimethylpent-1-ene and 2,4,4-Trimethylpent-2-ene 246-690-9 25167-70-8 2
Nonylphenol 246-672-0 25154-52-3 2
Tert-butyl methyl ether 216-653-1 1634-04-4 3
4-chloro-o-cresol 216-381-3 1570-64-5 1
Cryolite (Trisodium hexafluoroaluminate) 239-148-8 15096-52-3 3
1-(5,6,7,8-tetrahydro-3,5,5,6,8,8-hexamethyl-2-naph-thyl)ethan-1-one 216-133-4 1506-02-1 4
Ethyl acetoacetate 205-516-1 141-97-9 1
Cryolite (Trisodium hexafluoroaluminate) 237-410-6 13775-53-6 3
Tris[2-chloro-1-(chloromethyl)ethyl] phosphate (TDCP) 237-159-2 13674-87-8 4
tris(2-chloro-1-methylethyl) phosphate (TCPP) 237-158-7 13674-84-5 4
Chromium trioxide 215-607-8 1333-82-0 3
Disodium tetraborate, anhydrous 215-540-4 1330-43-4 4
Zinc oxide 215-222-5 1314-13-2 2
Nickel dinitrate 236-068-5 13138-45-9 4
Sodium hydroxide 215-185-5 1310-73-2 4
Diantimony trioxide 215-175-0 1309-64-4 4
Cadmium oxide 215-146-2 1306-19-0 3
Tetrachloroethylene 204-825-9 127-18-4 1
Octadecylamine 204-695-3 124-30-1 4



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