Information from the Existing Substances Regulation (ESR)

Before REACH entered into force, chemicals were regulated by a number of different regulations and directives. The Council Regulation (EEC) No 793/93 -- also known as the Existing Substances Regulation (ESR) -- was one of these. It introduced a comprehensive framework for the evaluation and control of "existing substances" (substances on the market before 1982). 

The ESR stated that the Commission, in consultation with the Member States, would regularly draw up lists of priority substances which require immediate attention because of their potential effects to human health or the environment. Between 1994 and 2007 (the entry into force of REACH), four such priority lists were published, with a total of 141 substances.

The table gives a complete overview on the risk assessments performed by the Member States for each of the 141 substances listed in the four priority lists.
 
Ethylbenzene 202-849-4 100-41-4 1
Styrene 202-851-5 100-42-5 1
Methenamine 202-905-8 100-97-0 2
Bis(hydroxylammonium) 233-118-8 10039-54-0 3
Boric acid, crude natural 233-139-2 10043-35-3 4
4,4'- Diaminodiphenylmethane (MDA) 202-974-4 101-77-9 1
Cobalt(II) dinitrate 233-402-1 10141-05-6
2-ethylhexyl acrylate 203-080-7 103-11-7 1
1,4-Dichlorobenzene (p-dichlorobenzene) 203-400-5 106-46-7 1
Buta-1,3-diene 203-450-8 106-99-0 1
Acrolein 203-453-4 107-02-8 1
Acrylonitrile 203-466-5 107-13-1 1
Dimethyldioctadecylammonium chloride 203-508-2 107-64-2 1
1-methoxypropan-2-ol (PGME) 203-539-1 107-98-2 4
Vinyl acetate 203-545-4 108-05-4 1
2-methoxy-1-methylethyl acetate (PGMA) 203-603-9 108-65-6 4
Toluene 203-625-9 108-88-3 2
Phenol 203-632-7 108-95-2 1
Pentane 203-692-4 109-66-0 2
2-methoxyethyl acetate 203-772-9 110-49-6 1
But-2-yne-1,4-diol 203-788-6 110-65-6 1
2-Ethoxyethanol 203-804-1 110-80-5 2
Cyclohexane 203-806-2 110-82-7 1
Piperazine 203-808-3 110-85-0 3
2-Ethoxyethyl acetate 203-839-2 111-15-9 2
2-butoxyethanol 203-905-0 111-76-2 4
2-(2-methoxyethoxy)ethanol (DEGME) 203-906-6 111-77-3 1
Boric acid 234-343-4 11113-50-1 4
Perboric acid, sodium salt 234-390-0 11138-47-9 3
2-butoxyethyl acetate 203-933-3 112-07-2 4
2-(2-butoxyethoxy)ethanol 203-961-6 112-34-5 1
(Z)-octadec-9-enylamine 204-015-5 112-90-3 4
Tris(2-chloroethyl)phosphate (TCEP) 204-118-5 115-96-8 2
Bis(pentabromophenyl) ether (decabromodiphenyl ether) (DecaBDE) 214-604-9 1163-19-5 1
Bis(2-ethylhexyl) phthalate (DEHP) 204-211-0 117-81-7 2
Dioctyl phthalate 204-214-7 117-84-0 1
Anthracene 204-371-1 120-12-7 3
1,2,4 Trichlorobenzene 204-428-0 120-82-1 2
2,4-Dinitrotoluene 204-450-0 121-14-2 4
Diphenylamine 204-539-4 122-39-4 3
1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethylin-deno[5,6-c]pyran 214-946-9 1222-05-5 4
1,4-dioxane 204-661-8 123-91-1 2
Octadecylamine 204-695-3 124-30-1 4
Tetrachloroethylene 204-825-9 127-18-4 1
Cadmium oxide 215-146-2 1306-19-0 3
Diantimony trioxide 215-175-0 1309-64-4 4
Sodium hydroxide 215-185-5 1310-73-2 4
Nickel dinitrate 236-068-5 13138-45-9 4
Zinc oxide 215-222-5 1314-13-2 2
Disodium tetraborate, anhydrous 215-540-4 1330-43-4 4
Chromium trioxide 215-607-8 1333-82-0 3
tris(2-chloro-1-methylethyl) phosphate (TCPP) 237-158-7 13674-84-5 4
Tris[2-chloro-1-(chloromethyl)ethyl] phosphate (TDCP) 237-159-2 13674-87-8 4
Cryolite (Trisodium hexafluoroaluminate) 237-410-6 13775-53-6 3
Ethyl acetoacetate 205-516-1 141-97-9 1
1-(5,6,7,8-tetrahydro-3,5,5,6,8,8-hexamethyl-2-naph-thyl)ethan-1-one 216-133-4 1506-02-1 4
Cryolite (Trisodium hexafluoroaluminate) 239-148-8 15096-52-3 3
4-chloro-o-cresol 216-381-3 1570-64-5 1
Tert-butyl methyl ether 216-653-1 1634-04-4 3
Nonylphenol 246-672-0 25154-52-3 2
Reaction mass of 2,4,4-Trimethylpent-1-ene and 2,4,4-Trimethylpent-2-ene 246-690-9 25167-70-8 2
Hexabromocyclododecane (HBCDD) 247-148-4 25637-99-4 2
Methylenediphenyl diisocyanate 247-714-0 26447-40-5 3
Tris(nonylphenyl) phosphite (TNPP) 247-759-6 26523-78-4 4
Di-isodecyl phthalate 247-977-1 26761-40-0 2
Di-isononyl phthalate 249-079-5 28553-12-0 2
2,3-epoxypropyltrimethylammonium chloride 221-221-0 3033-77-0 3
Pentanol 250-378-8 30899-19-5 3
Diphenyl ether, pentabromo derivative 251-084-2 32534-81-9 2
Diphenyl ether, octabromo derivative 251-087-9 32536-52-0 1
(3-chloro-2-hydroxypropyl) 222-048-3 3327-22-8 3
Nickel carbonate 222-068-2 3333-67-3 4
V6 (2,2-bis(chloromethyl) trimethylene bis[bis(2-chloroethyl)phosphate]) 253-760-2 38051-10-4 4
Trisodium nitrilotriacetate 225-768-6 5064-31-3 3
Zinc distearate, Fatty acids, C16-18, zinc salts
209-151-9
293-049-4
557-05-1
91051-01-3
2
Edetic acid 200-449-4 60-00-4 1
Amines, hydrogenated tallow alkyl 262-976-6 61788-45-2 4
Amines, coco alkyl 262-977-1 61788-46-3 4
Amines, tallow alkyl 263-125-1 61790-33-8 2
Aniline 200-539-3 62-53-3 1
Tetrasodium ethylenediaminetetraacetate 200-573-9 64-02-8 1
Distillates (coal tar) 266-027-7 65996-92-1 1
Pitch, coal tar, high temp. 266-028-2 65996-93-2 3
Chloroform 200-663-8 67-66-3 2
Benzene, C10-13-alkyl derivs 267-051-0 67774-74-7 1
1,2-Benzenedicarboxylic acid, di-C8-10-branched alkyl esters, C9-rich 271-090-9 68515-48-0 2
1,2-Benzenedicarboxylic acid, di-C9-11-branched alkyl esters, C10-rich 271-091-4 68515-49-1 2
Propan-1-ol 200-746-9 71-23-8 2
Benzene 200-753-7 71-43-2 1
Nickel 231-111-4 7440-02-0 3
Cadmium 231-152-8 7440-43-9 3
Zinc 231-175-3 7440-66-6 2
Acetonitrile 200-835-2 75-05-8 1
Chlorodifluoromethane 200-871-9 75-45-6 2
Methyloxirane (Propylene oxide) 200-879-2 75-56-9 2
TBHP (Hydroperoxide, 1,1-Dimethylethyl) 200-915-7 75-91-2 3
Zinc chloride 231-592-0 7646-85-7 2
Hydrogen fluoride 231-634-8 7664-39-3 1
Sodium hypochlorite 231-668-3 7681-52-9 2
Hexachlorocyclopentadiene 201-029-3 77-47-4 4
Dimethyl sulphate 201-058-1 77-78-1 2
Nickel dichloride 231-743-0 7718-54-9 4
Hydrogen peroxide 231-765-0 7722-84-1 2
Zinc sulphate 231-793-3 7733-02-0 2
Sodium chromate 231-889-5 7775-11-3 3
Potassium dichromate 231-906-6 7778-50-9 3
Trizinc bis(orthophosphate) 231-944-3 7779-90-0 2
Chlorine 231-959-5 7782-50-5 3
Aluminium fluoride 232-051-1 7784-18-1 4
Nickel sulphate 232-104-9 7786-81-4 3
Ammonium dichromate 232-143-1 7789-09-5 3
Sodium dichromate 234-190-3
7789-12-0
10588-01-9
3
Calcium fluoride 232-188-7 7789-75-5 4
Trichloroethylene 201-167-4 79-01-6 1
Acrylamide 201-173-7 79-06-1 1
Acrylic acid 201-177-9 79-10-7 1
Chloroacetic acid 201-178-4 79-11-8 3
Methyl acetate 201-185-2 79-20-9 1
Methacrylic acid 201-204-4 79-41-4 1
2,2,6,6-tetrabromo-4,4-isopropylidenediphenol 201-236-9 79-94-7 4
Part I
Part II
Bisphenol A,4,4'-isopropylidenediphenol 201-245-8 80-05-7 3
Methyl methacrylate 201-297-1 80-62-6 1
4-tert-butyl-2,6-dimethyl-3,5-dinitroacetophenone 201-328-9 81-14-1 3
5-tert-butyl-2,4,6-trinitro-m-xylene (Musk xylene) 201-329-4 81-15-2 3
Dibutyl phthalate 201-557-4 84-74-2 1
Phenol, 4-nonyl-, branched 284-325-5 84852-15-3 2
Benzyl butyl phthalate (BBP) 201-622-7 85-68-7 3
Alkanes, C10-13, chloro (Short Chain Chlorinated Paraffins) 287-476-5 85535-84-8 1
Alkanes, C14-17, chloro (MCCP, Medium chained chlorinated paraffins) 287-477-0 85535-85-9 3
1-vinyl-2-pyrrolidone 201-800-4 88-12-0 2
2-nitrotoluene 201-853-3 88-72-2 4
2-Methoxyaniline,o-Anisidine 201-963-1 90-04-0 2
Naphthalene 202-049-5 91-20-3 1
N-cyclohexylbenzothiazole- 2-sulphenamide 202-411-2 95-33-0 2
3,4-dichloroaniline 202-448-4 95-76-1 1
4-methyl-m-phenylenediamine (toluene-2,4-diamine) 202-453-1 95-80-7 1
2-furaldehyde 202-627-7 98-01-1 2
p-tert-butylphenol 202-679-0 98-54-4 4
4-tert-butylbenzoic acid 202-696-3 98-73-7 4
Cumene 202-704-5 98-82-8 1
Nitrobenzene 202-716-0 98-95-3 3
2-methoxy-2-methylbutane 213-611-4 994-05-8 4



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