Summary of Classification and Labelling
Notified classification and labelling
General Information
EC / List no.

EC: European Community number/ List no.: List number assigned by ECHA.

List Numbers are purely technical identifiers for processing a submission via REACH-IT. More information: https://echa.europa.eu/information-on-chemicals/registered-substances/information

Name CAS Number
The CAS number associated with this substance in the EC Inventory and/or REACH-IT is reported here. In some cases, e.g. for differently hydrated forms of the same substance, alternative CAS numbers have been notified. In those cases, the additional CAS numbers are published in the column “additional notified information” below.
603-618-4 10H-Thieno(2,3-b)(1,5)benzodiazepine, 2-methyl-4-(4-methyl-1-piperazinyl)- 132539-06-1

Notified classification and labelling according to CLP criteria
Classification Labelling Specific Concentration limits, M-Factors Notes Classification affected by Impurities / Additives

This check appears when a notifier has indicated that an impurity or an additive present in the substance impacts the notified classification. ECHA cannot reveal the identity of the impurity/additive or determine the exact impact it has on the classification.

Additional Notified Information

State/form: The notified state/form of the substance for all notifications classifying in this manner is reported under this link. Additional CAS number(s): Occasionally, a notification contains a different CAS number than the one reported under the general information section above. In those cases, all different notified CAS numbers associated with the aggregated classification are reported under this link. IUPAC name(s): Publicly available IUPAC names from all notifications classifying in this manner are reported under this link.

Number of Notifiers

This number indicates how many companies notified this classification. All members of a REACH registration joint submission and all participants in a group of manufacturers/importers who notified are counted. The grouping is done automatically with no manual verification.

Joint Entries

This check appears when a classification comes from a lead dossier of a REACH registration joint submission. When a member submits a classification separately under Article 11(3) of REACH (opt-out), this classification is displayed separately and not marked as a joint entry.

Hazard Class and Category Code(s) Hazard Statement Code(s) Hazard Statement Code(s) Supplementary Hazard Statement Code(s) Pictograms, Signal Word Code(s)
Skin Irrit. 2 H315 H315 GHS07
Wng
23 View details
Eye Irrit. 2 H319 H319
Acute Tox. 3 H301 H301 GHS08
GHS06
Dgr
State/Form
IUPAC Names
2 View details
Skin Irrit. 2 H315 H315
Skin Sens. 1 H317 H317
Eye Irrit. 2 H319 H319
Carc. 2 H351 H351
  H301 GHS07
GHS06
Dgr
State/Form
1 View details
  H317
  H319
Acute Tox. 3 H301 H301 GHS08
GHS06
GHS07
Dgr
State/Form
IUPAC Names
1 View details
Eye Irrit. 2 H319 H319
Repr. 2 H361 (Fertility) H361
STOT RE 2 H373 (Blood) H373
  H302 GHS07
Wng
1 View details
Acute Tox. 4 H302 H302 GHS08
GHS07
Wng
State/Form
1 View details
Skin Sens. 1 H317 H317
Eye Irrit. 2 H319 H319
STOT SE 3 H336 (CNS) H336 (CNS)
Carc. 2 H351 H351
Repr. 2 H361 (fd) H361 (df)
Lact. H362 H362
Aquatic Chronic 4 H413 H413
Acute Tox. 3 H301 H301 GHS09
GHS08
GHS06
Dgr
M(Chronic)=1
State/Form
IUPAC Names
1 View details
Skin Sens. 1 H317 H317
Eye Irrit. 2 H319 H319
STOT SE 3 H336 (H336: May cause...) H336 (H336: May cause...)
STOT RE 2 H373 (blood) H373 (blood)
Aquatic Chronic 1 H410 H410
Acute Tox. 3 H301 H301 GHS09
GHS08
GHS07
GHS06
Dgr
IUPAC Names 1 View details
Skin Irrit. 2 H315 H315
Skin Sens. 1 H317 H317
Eye Irrit. 2 H319 H319
Carc. 2 H351 H351
Aquatic Chronic 2 H411 H411
Acute Tox. 3 H301 H301 GHS06
GHS07
Dgr
State/Form
IUPAC Names
1 View details
Skin Sens. 1 H317 H317
Eye Irrit. 2 H319 H319
Acute Tox. 3 H301 H301 GHS06
Dgr
IUPAC Names 1 View details
Skin Irrit. 2 H315 H315
Eye Irrit. 2 H319 H319
Acute Tox. 3 H301 H301 GHS09
GHS08
GHS06
Dgr
M(Chronic)=1
State/Form
IUPAC Names
1 View details
Skin Sens. 1 H317 H317
Eye Irrit. 2A H319 H319
STOT SE 3 H336 (H336: May cause...) H336 (H336: May cause...)
STOT RE 2 H373 (blood) H373 (blood)
Aquatic Chronic 1 H410 H410
Acute Tox. 4 H332 H332 GHS07
Wng
State/Form
IUPAC Names
1 View details
Aquatic Chronic 3 H412 H412
Acute Tox. 3 H301 H301 GHS09
GHS08
GHS06
Dgr
M(Chronic)=1
State/Form
IUPAC Names
1 View details
Skin Sens. 1 H317 H317
Eye Irrit. 2 H319 H319
STOT SE 3 H336 (Narcotic Effect...) H336
STOT RE 2 H373 (Blood) H373
Aquatic Chronic 1 H410 H410
Acute Tox. 3 H301 H301 GHS09
GHS08
GHS06
Dgr
M(Chronic)=1
State/Form
IUPAC Names
1 View details
Skin Sens. 1 H317 H317
Eye Irrit. 2 H319 H319
STOT SE 3 H336 (Narcotic effect...) H336
STOT RE 2 H373 (Blood) H373
Aquatic Chronic 1 H410 H410
Acute Tox. 3 H301 H301 GHS06
Dgr
IUPAC Names 1 View details
Skin Sens. 1 H317 H317
Eye Irrit. 2 H319 H319
STOT SE 3 H336 (unknown) H336
Acute Tox. 3 H301 H301 GHS07
GHS06
Dgr
State/Form
IUPAC Names
1 View details
Skin Irrit. 2 H315 H315
Skin Sens. 1 H317 H317
Eye Irrit. 2 H319 H319
Acute Tox. 3 H301 H301 GHS08
GHS06
Dgr
State/Form
IUPAC Names
1 View details
Repr. 1B H360 H360
STOT RE 2 H373 (liver, central ...) (oral and inhala...) H373
Acute Tox. 3 H301 H301 GHS07
GHS06
Dgr
IUPAC Names 1 View details
Skin Sens. 1 H317 H317
Eye Irrit. 2 H319 H319
STOT SE 3 H336 (Category 3 narc...) H336
Acute Tox. 3 H301 H301 GHS08
GHS06
Dgr
1 View details
Skin Irrit. 2 H315 H315
Skin Sens. 1 H317 H317
Eye Irrit. 2 H319 H319
STOT SE 3 H336 (not specified) H336
STOT RE 2 H373 (not specified) H373

Number of Aggregated Notifications: 19