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Annex III inventory

Annex III inventory

ECHA compiled an inventory of substances likely to meet the criteria of Annex III to the REACH Regulation. The aim is to support registrants in identifying whether reduced minimum information requirements or a full Annex VII information set is required.

The inventory was produced using publicly available databases with experimental data and by using (Q)SAR model results. Indications for hazardous toxicological or ecotoxicological properties together with information on uses and other available relevant information have to be compared with the criteria in Annex III.

The fact that a substance is not in this list does not necessarily mean that the criteria for Annex III are not met. Likewise, if a substance is on this inventory, a registrant can still benefit from the reduced information requirements if it is justified.

Note that the inventory is not a tool for classification, it only shows indications for concern. For instance, the fact that a substance is indicated as "Suspected mutagen" does not mean that ECHA considers it as a classified mutagen. All evidence should be taken into account before concluding on the need for classification.

Last updated 18 May 2016. Database contains 64899 unique substances/entries.
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10027-06-2
Harmonised classification for acute toxicity
Harmonised classification for skin sensitisation
Details
620-411-4
123748-85-6
Harmonised classification for acute toxicity
Harmonised classification for eye irritation
Harmonised classification for respiratory sensitisation
Harmonised classification for specific target organ toxicity
Details
412-760-4
5470-82-6
Harmonised classification for acute toxicity
Harmonised classification for aquatic toxicity
Harmonised classification for skin sensitisation
Details
216-055-0
1484-13-5
Harmonised classification for acute toxicity
Harmonised classification for aquatic toxicity
Harmonised classification for mutagenicity
Harmonised classification for skin sensitisation
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Details
614-054-3
67375-30-8
Harmonised classification for acute toxicity
Harmonised classification for aquatic toxicity
Harmonised classification for specific target organ toxicity
Suspected bioaccumulative
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
265-294-7
64969-36-4
Suspected acutely toxic via the oral route
Harmonised classification for acute toxicity
Harmonised classification for aquatic toxicity
Harmonised classification for carcinogenicity
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected toxic for reproduction
Details
603-964-6
136465-81-1
Harmonised classification for acute toxicity
Harmonised classification for aquatic toxicity
Harmonised classification for eye damage
Suspected hazardous to the aquatic environment
Details
209-322-8
569-64-2
Suspected acutely toxic via the oral route
Harmonised classification for acute toxicity
Harmonised classification for aquatic toxicity
Harmonised classification for eye damage
Harmonised classification for reprotoxicity
Suspected carcinogen
Suspected mutagen
Suspected persistent in the environment
Details
208-520-1
531-86-2
Suspected acutely toxic via the oral route
Harmonised classification for acute toxicity
Harmonised classification for aquatic toxicity
Harmonised classification for carcinogenicity
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected toxic for reproduction
Details
680-295-6
99817-36-4
Harmonised classification for acute toxicity
Harmonised classification for aquatic toxicity
Harmonised classification for eye damage
Harmonised classification for skin sensitisation
Details
639-798-6
89544-40-1
Harmonised classification for acute toxicity
Harmonised classification for aquatic toxicity
Harmonised classification for eye damage
Details
638-811-2
1862-07-3
Harmonised classification for acute toxicity
Harmonised classification for aquatic toxicity
Harmonised classification for skin corrosion
Details
629-003-0
162241-33-0
Harmonised classification for acute toxicity
Harmonised classification for aquatic toxicity
Harmonised classification for eye damage
Harmonised classification for skin sensitisation
Harmonised classification for specific target organ toxicity
Details
639-262-1
137234-87-8
Harmonised classification for acute toxicity
Harmonised classification for aquatic toxicity
Details
687-187-8
17193-28-1
Harmonised classification for acute toxicity
Harmonised classification for eye damage
Harmonised classification for specific target organ toxicity
Details
687-584-6
97384-48-0
Harmonised classification for acute toxicity
Harmonised classification for aquatic toxicity
Details
687-585-1
2833-30-9
Harmonised classification for acute toxicity
Harmonised classification for skin corrosion
Harmonised classification for skin sensitisation
Harmonised classification for specific target organ toxicity
Suspected hazardous to the aquatic environment
Suspected skin sensitiser
Details
695-657-9
147086-81-5
Harmonised classification for acute toxicity
Details
804-253-5
618-26-8
Harmonised classification for acute toxicity
Harmonised classification for aquatic toxicity
Harmonised classification for eye damage
Harmonised classification for skin sensitisation
Harmonised classification for specific target organ toxicity
Details
623-924-1
17630-75-0
Harmonised classification for acute toxicity
Harmonised classification for aquatic toxicity
Harmonised classification for reprotoxicity
Harmonised classification for skin sensitisation
Details
636-864-6
35687-90-2
Harmonised classification for acute toxicity
Details
629-290-2
107667-02-7
Harmonised classification for acute toxicity
Harmonised classification for aquatic toxicity
Harmonised classification for skin corrosion
Details
629-169-4
95500-19-9
Harmonised classification for acute toxicity
Harmonised classification for skin corrosion
Details
629-598-7
57044-25-4
Harmonised classification for acute toxicity
Harmonised classification for carcinogenicity
Harmonised classification for mutagenicity
Harmonised classification for reprotoxicity
Harmonised classification for skin corrosion
Suspected mutagen
Details
638-823-8
98769-75-6
Harmonised classification for acute toxicity
Harmonised classification for aquatic toxicity
Harmonised classification for eye damage
Details
640-399-4
19060-15-2
Harmonised classification for acute toxicity
Harmonised classification for aquatic toxicity
Harmonised classification for skin corrosion
Harmonised classification for skin sensitisation
Details
642-873-6
61721-07-1
Harmonised classification for acute toxicity
Harmonised classification for aquatic toxicity
Harmonised classification for skin corrosion
Harmonised classification for skin sensitisation
Details
801-876-4
3508-98-3
Harmonised classification for acute toxicity
Harmonised classification for aquatic toxicity
Details
673-692-0
70918-74-0
Harmonised classification for acute toxicity
Harmonised classification for aquatic toxicity
Harmonised classification for specific target organ toxicity
Details
670-923-7
77227-99-7
Harmonised classification for acute toxicity
Harmonised classification for aquatic toxicity
Details
680-239-0
112941-26-1
Harmonised classification for acute toxicity
Harmonised classification for eye irritation
Details
680-305-9
54417-53-7
Harmonised classification for acute toxicity
Harmonised classification for aquatic toxicity
Details
690-534-6
149564-66-9
Harmonised classification for acute toxicity
Harmonised classification for aquatic toxicity
Harmonised classification for eye damage
Details
265-748-4
65405-96-1
Harmonised classification for acute toxicity
Harmonised classification for aquatic toxicity
Harmonised classification for carcinogenicity
Harmonised classification for mutagenicity
Harmonised classification for reprotoxicity
Harmonised classification for respiratory sensitisation
Harmonised classification for skin sensitisation
Harmonised classification for specific target organ toxicity
Details
630-839-3
147027-04-1
Harmonised classification for acute toxicity
Harmonised classification for eye damage
Harmonised classification for skin sensitisation
Details
265-610-3
65195-55-3
Harmonised classification for acute toxicity
Harmonised classification for aquatic toxicity
Harmonised classification for reprotoxicity
Harmonised classification for specific target organ toxicity
Suspected persistent in the environment
Suspected toxic for reproduction
Details
615-339-5
71751-41-2
Harmonised classification for acute toxicity
Harmonised classification for aquatic toxicity
Harmonised classification for reprotoxicity
Harmonised classification for specific target organ toxicity
Suspected bioaccumulative
Details
250-241-2
30560-19-1
Harmonised classification for acute toxicity
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Details
607-353-5
24294-01-7
Harmonised classification for acute toxicity
Harmonised classification for aquatic toxicity
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected skin sensitiser
Details
603-921-1
135410-20-7
Harmonised classification for acute toxicity
Harmonised classification for aquatic toxicity
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Details
206-121-7
302-27-2
Harmonised classification for acute toxicity
Suspected hazardous to the aquatic environment
Suspected persistent in the environment
Details
240-110-8
15972-60-8
Suspected acutely toxic via the oral route
Harmonised classification for acute toxicity
Harmonised classification for aquatic toxicity
Harmonised classification for carcinogenicity
Harmonised classification for skin sensitisation
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected skin sensitiser
Details
204-123-2
116-06-3
Harmonised classification for acute toxicity
Harmonised classification for aquatic toxicity
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected toxic for reproduction
Details
206-215-8
309-00-2
Harmonised classification for acute toxicity
Harmonised classification for aquatic toxicity
Harmonised classification for carcinogenicity
Harmonised classification for specific target organ toxicity
Suspected bioaccumulative
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected skin irritant
Suspected skin sensitiser
Suspected toxic for reproduction
Details
209-542-4
584-79-2
Harmonised classification for acute toxicity
Harmonised classification for aquatic toxicity
Suspected bioaccumulative
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected skin sensitiser
Suspected toxic for reproduction
Details
202-270-7
93-71-0
Harmonised classification for acute toxicity
Harmonised classification for aquatic toxicity
Harmonised classification for eye irritation
Suspected carcinogen
Suspected hazardous to the aquatic environment
Suspected mutagen
Suspected persistent in the environment
Suspected skin irritant
Suspected skin sensitiser
Suspected toxic for reproduction
Details
615-303-9
71550-12-4
Harmonised classification for acute toxicity
Harmonised classification for skin sensitisation
Details
244-088-0
20859-73-8
Harmonised classification for acute toxicity
Harmonised classification for aquatic toxicity
Details
262-977-1
61788-46-3
Harmonised classification for acute toxicity
Harmonised classification for aquatic toxicity
Harmonised classification for aspiration toxicity
Harmonised classification for skin corrosion
Harmonised classification for specific target organ toxicity
Details
263-125-1
61790-33-8
Harmonised classification for acute toxicity
Harmonised classification for aquatic toxicity
Harmonised classification for aspiration toxicity
Harmonised classification for skin corrosion
Harmonised classification for specific target organ toxicity
Details

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