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Diss Factsheets
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EC number: 600-028-9 | CAS number: 1001254-87-0
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2001-04-19 to 2001-07-31
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Guideline Study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.4-D (Determination of the "Ready" Biodegradability - Manometric Respirometry Test)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- - Source of inoculum/activated sludge: communal sewage plant Groß-Zimmern, Germany
- Preparation of inoculum for exposure: activated sludge was washed by centrifugation and the supernatant liquid phase was decanted; the solid material was resuspended in tap water and again centrifuged; this procedure was repeated twice; an aliquot of the final sludge suspension was weighed, dried and the ration of wet sludge to its dry weight was determined. Based on this ratio,
- Concentration of sludge: 1.5 g /L dw - Duration of test (contact time):
- 28 d
- Initial conc.:
- 102.1 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- TEST CONDITIONS
- Composition of medium: according to OECD 301 A
- Test temperature: 21-22 °C
- pH: 7.6
- pH adjusted: no
- Suspended solids concentration: 30 mg/L
- Continuous darkness: yes
TEST SYSTEM
- Culturing apparatus: flasks, 500 mL, incubated in a cllimatic chamber under continuous stirring
- Number of culture flasks/concentration: 2 flasks containing the test substance, 2 inoculum blank, 1 procedure control, 1 abiotic control, 1 toxicity control
- Measuring equipment: BSB/BOD-Sensor-System
- amounts of test item and reference substance were directly weighted into the test flasks and solutions were stirred during the exposure period
SAMPLING
- Sampling frequency: at least once per day
CONTROL AND BLANK SYSTEM
- Inoculum blank: 2
- Abiotic sterile control: 1
- Toxicity control: 1 - Reference substance:
- aniline
- Parameter:
- % degradation (O2 consumption)
- Value:
- 0
- Sampling time:
- 28 d
- Details on results:
- After correction of teh mean biochmical oxygen demand of the inoculum controls at the end of the 28-day exposure period degradation rates of -4% based on ThODNH4, were found.
- Results with reference substance:
- The reference item Aniline was sufficiently degraded: 87% after 14 days and 105% after 28 days of incubation.
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- under test conditions no biodegradation observed
- Conclusions:
- The test substance can be considered to be not ready biodegradable
- Executive summary:
The biodegradability of the test item was examined in a "Manometric Respirometry Test"-test according to EU-Method C.4 -D and OECD 301 F (IBACON GmbH 2001). Oxygen consumption was measured continuously (at least daily) over a period of 28 days. The test item was observed to be "not ready biodegradable" under the present test conditions (0% biodegradation within 28 days). The study was assessed as "reliable without restriction".
Reference
Description of key information
The biodegradability of the test item was examined in a "Manometric Respirometry Test"-test according to EU-Method C.4 -D and OECD 301 F (IBACON GmbH 2001). Oxygen consumption was measured continuously (at least daily) over a period of 28 days.
Key value for chemical safety assessment
- Biodegradation in water:
- not biodegradable
Additional information
The test item was observed to be "not ready biodegradable" under the present test conditions (0% biodegradation within 28 days).
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